Patent
Cell sorting device and method
Yu-Hwa Lo,Yi Gu +1 more
- 16 Sep 2019
TL;DR: In this paper, a cell sorting system consisting of an imaging device including a beam scanner scanning a beam along a first direction to obtain a cell image data including fluorescent information or cell image information of a cell, the beam applied to the cell flowing in a channel along a second direction with an angle to the first direction was provided.
read more
Abstract: A cell sorting system is provided to comprise: an imaging device including a beam scanner scanning a beam along a first direction to obtain a cell image data including fluorescent information or cell image information of a cell, the beam applied to the cell flowing in a channel along a second direction with an angle to the first direction; a data processing and control device in communication with the imaging device, the data processing and control device including a processor configured to process the cell image data obtained by the imaging device to determine one or more properties associated with the cell from the processed cell image data and to produce a control command based on a comparison of the determined one or more properties with a sorting criteria, and a cell sorting device in communication with the imaging device and the data processing and control device.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
References
Patent
Particle or cell analyzer and method
Philippe J. Goix,Paul J. Lingane,Janette T. Phi-Wilson +2 more
- 05 Sep 2001
TL;DR: In this article, a particle analyzer in which tagged particles to be analyzed are drawn through a suspended capillary tube where a predetermined volume in the capillary tubes is illuminated and the fluorescent illumination emitted by tagged particles is detected and the output signals from the fluorescent detectors and scatter detector are processed to provide an analysis of the particles.
104
Patent
Apparatus and methods for fluorescence imaging using radiofrequency-multiplexed excitation
Eric D. Diebold,Bahram Jalali,Brandon Buckley +2 more
- 09 Jan 2014
TL;DR: In this paper, a phase-engineered radio frequency comb was used to generate multiple deflected optical beams possessing a range of output angles and frequency shifts for fluorescence imaging using a single photomultiplier tube and digital phase-coherent signal recovery.
20
Patent
Cell Sorting Using A High Throughput Fluorescence Flow Cytometer
Eric D. Diebold,Keegan Owsley,Jonathan Lin +2 more
- 17 Mar 2017
TL;DR: In this article, a method of sorting cells in a flow cytometry system is disclosed, which includes illuminating a cell with radiation having at least two optical frequencies shifted from one another by a radiofrequency to elicit fluorescent radiation from the cell, detecting the fluorescent radiation to generate temporal fluorescence data, and processing the temporal fluorescent data to arrive at a sorting decision regarding the cell without generating an image (i.e., a pixel-by-pixel image) of the cell based on the fluorescence.
15
Patent
Image-based cell sorting systems and methods
Yu-Hwa Lo,Yuanyuan Han,Yi Gu,Ce Zhang +3 more
- 09 Jun 2017
TL;DR: In this article, the authors present a system, devices and methods for image-based sorting of particles in a flow system, including cells of a flow cytometer and an actuator to direct the particle into one of a plurality of output paths of the particle flow device in real-time.
3