Journal Article10.1016/J.ECHO.2005.10.021
Cardiac resynchronization therapy and the emerging role of echocardiography (part 1): indications and results from current studies.
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TL;DR: The applications of CRT are discussed, including results of clinical trials and the current experience using echocardiography, and the practical aspects of obtaining eChocardiographic data in patients who are potential candidates for CRT and optimization of pacemaker settings after device implantation are addressed.
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Abstract: Cardiac resynchronization therapy (CRT) has been established as an adjunctive treatment for patients with left ventricular systolic dysfunction and medically refractory heart failure with a wide QRS interval. Echocardiography can be used to determine the response in left ventricular structure and function after device implantation and emerging evidence as a method for selection of patients who may derive clinical benefit from CRT. This review discusses the applications of CRT, including results of clinical trials and the current experience using echocardiography. Part 2 will address the practical aspects of obtaining echocardiographic data in patients who are potential candidates for CRT and optimization of pacemaker settings after device implantation.
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Citations
Circulating microRNA changes in heart failure patients treated with cardiac resynchronization therapy: responders vs. non-responders
Raffaele Marfella,Clara Di Filippo,Nicoletta Potenza,Celestino Sardu,Maria Rosaria Rizzo,Mario Siniscalchi,Emilio Musacchio,Michelangela Barbieri,Ciro Mauro,Nicola Mosca,Francesco Solimene,Maria Teresa Mottola,Aniello Russo,Francesco Rossi,Giuseppe Paolisso,Michele D'Amico +15 more
TL;DR: This work studied whether LV reverse remodelling after CRT was associated with changes of circulating miRNAs in patients with heart failure (HF) and dyssynchrony.
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Doppler echocardiography and myocardial dyssynchrony: a practical update of old and new ultrasound technologies.
TL;DR: There is not no consensus about the best approach and the best ultrasound parameter for selecting candidates to CRT and ECG representation of abnormal cardiac conduction still remains as the main criterion in guidelines.
Cardiac resynchronization therapy: variations in echo-guided optimized atrioventricular and interventricular delays during follow-up.
Cinzia Valzania,Mauro Biffi,Cristian Martignani,Igor Diemberger,Matteo Bertini,Matteo Ziacchi,Letizia Bacchi,Guido Rocchi,Claudio Rapezzi,Angelo Branzi,Giuseppe Boriani +10 more
TL;DR: Echocardiographic optimization of AV and VV delay is associated with broad intraindividual variability during follow‐up and reveals a nonconcordance with previous values and provides increases in forward stroke volume.
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Predicting Response to Cardiac Resynchronization Therapy with Cross-Correlation Analysis of Myocardial Systolic Acceleration: A New Approach to Echocardiographic Dyssynchrony Evaluation
TL;DR: XCA significantly improves the assessment of intraventricular dyssynchrony, and dyss synchrony by this method is associated with positive long-term response to CRT.
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O ecocardiograma na terapia de ressincronização cardíaca
TL;DR: A terapia de resincronizacao cardiaca (TRC) as discussed by the authors has proven to be uma opcao efetiva nos pacients com insuficiencia cardiaca avancada.
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- 14 Apr 2005
TL;DR: Cardiac resynchronization has been shown to reduce symptoms and improve left ventricular function in patients with heart failure due to systolic dysfunction and cardiac dyssynchrony.
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TL;DR: Metoprolol controlled release/extended release (CR/XL) once daily in addition to standard therapy improved survival and the drug was well tolerated.
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