Journal Article10.1016/0092-8674(76)90128-8
Capping of eucaryotic mRNAs
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About: This article is published in Cell. The article was published on 01 Dec 1976.
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Citations
Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication
Natacha S. Ogando,Priscila El Kazzi,Jessika C. Zevenhoven-Dobbe,Brenda w. Bontes,Alice Decombe,Clara C. Posthuma,Volker Thiel,Bruno Canard,François Ferron,Etienne Decroly,Eric J. Snijder +10 more
TL;DR: In this article, structural, biochemical, and virological data were integrated to assess the importance of conserved N7-MTase residues for nsp14s enzymatic activities and virus viability.
Analyses of mRNA Cleavage by RelE and the Role of tRNA Methyltransferase TrmD Using Bacterial Ribosome Profiling
Jae Yeon Hwang
- 01 Jan 2016
TL;DR: The mechanism of translating mRNA cleavage by endoribonuclease RelE in vivo is reported and ribosome profiling technique successfully observed significant difference on translation process when codons interact with anticodons of tRNAs lacking mG37.
Hormone: Eigenschaften und Mechanismen ihrer Wirkung
H. Stolecke
- 01 Jan 1997
TL;DR: Hormone sind Botenstoffe, die masgeblich an der regulativen Verknupfung von Stoffwechselleistungen innerhalb eines komplexen biologischen Systems beteiligt sind Hormone haben eine Signalfunktion; Organe oder Zellen mit entsprechender „Adresse“ nehmen das Signal auf and setzen es in eine metabolische Funktion um
Neue RNA-Moleküle und die Regulation der Genexpression auf Translationsebene
Ulrich-Axel Bommer,Thomas Preiss +1 more
TL;DR: In this article, the authors present a model of the 5'-untranslatierten region (5'-UTR) of RNA-Moleküle.
5′-CAPPING AND EUKARYOTIC mRNA FUNCTION
Aaron J. Shatkin,Nahum Sonenberg,Y. Furuichi +2 more
- 01 Jan 1979
TL;DR: This chapter highlights that capped m RNAs are degraded more slowly than the corresponding uncapped mRNAs in HeLa cell nuclear and cytoplasmic fractions, in cell-free protein synthesizing systems from wheat germ and mouse L cells, and in microinjected Xenopus oocytes.
References
5'-Terminal 7-methylguanosine in eukaryotic mRNA is required for translation.
TL;DR: Unmethylated reovirus and VSV mRNAs are specifically methylated to form 5′-terminal structures of the type, m7G ( 5′)ppp (5′) N by protein synthesizing extracts prepared from wheat germ and mouse L cells.
503
Modified nucleosides and bizarre 5'-termini in mouse myeloma mRNA.
Jerry M. Adams,Suzanne Cory +1 more
TL;DR: Messenger RNAs from mouse myeloma cells contain N6-methyl adenosine and novel 5′ termini having 7-methylguanosine in a 5′, 5′triphosphate linkage with ribose-methylated nucleosides, suggesting a general feature of mRN A in eukaryotes.
456
Translational Control of Protein Synthesis
TL;DR: A comparison of the rates of adoption and adoption of different approaches to translation of EUKARYOTIC mRNAs in the US and Europe over the past 50 years reveals a clear trend towards adoption of a more holistic approach.
453
Processing of RNA.
TL;DR: This research attacked the prokaryote-prokaryotes “ cellular “spatially aggregating” mechanism with a “knock-on” effect that results in knock-on effects that affect the ability of these cells to “talk” to each other.
453
Purification of mRNA guanylyltransferase and mRNA (guanine-7-) methyltransferase from vaccinia virions.
TL;DR: Under denaturing conditions of sodium dodecyl sulfate-polyacrylamide gel electrophoresis two majorpolypeptides were detected in purified enzyme preparations and suggested they were polypeptide components of the 127,000 molecular weight enzyme system.
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