Journal Article10.1016/S0007-1935(05)80170-8
Canine cystinuria: an extended study on the effects of 2-mercaptopropionylglycine on cystine urolithiasis and urinary cystine excretion.
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TL;DR: It was concluded that 2-MPG is a satisfactory alternative treatment for cystinuric dogs and has a good prophylactic effect, shown as a change in the rate of urolith formation from on average 6 months before to 17 months during 2-MPT treatment.
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About: This article is published in British Veterinary Journal. The article was published on 01 Jan 1993. The article focuses on the topics: Cystine Urolithiasis & Cystinuria.
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Citations
Canine cystinuria: polymorphism in the canine SLC3A1 gene and identification of a nonsense mutation in cystinuric Newfoundland dogs
Paula S. Henthorn,Junlong Liu,Tanya Gidalevich,Jikang Fang,Margret L. Casal,Donald F. Patterson,Urs Giger +6 more
TL;DR: The canine homologue of human type I cystinuria provides the opportunity to use a large animal model to investigate molecular approaches for the treatment of cystine urolithiasis and other renal tubular diseases.
63
•Journal Article
A review on urolithiasis in dogs and cats.
TL;DR: Past and recent literature on urolithiasis was reviewed for information on anatomical occurrence, physiology of urine formation, prevalence, mineral composition, clinical signs, laboratory findings, dissolution therapy, surgery and prevention of the disease.
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Canine cystine urolithiasis. Cause, detection, treatment, and prevention.
Carl A. Osborne,Sherry L. Sanderson,Jody P. Lulich,Joseph W. Bartges,Lisa K. Ulrich,Lori A. Koehler,Kathleen A. Bird,Laura L. Swanson +7 more
TL;DR: In this paper, 67 breeds of dogs were identified, including English Bulldogs, Dachshunds, Mastiffs, and Newfoundlands, and various recommendations for dissolution of cystine uroliths include various combinations of diet modification, diuresis, administration of 2-MPG, and alkalinization of urine.
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Cystinuria in the dog: clinical studies during 14 years of medical treatment.
A. Hoppe,Torsten Denneberg +1 more
TL;DR: In dogs with re-formed Cystine uroliths, dissolution may be induced by increasing the tiopronin dosage to 40 mg/kg body weight per day, and in dogs with a low urolith recurrence rate and low urinary cystine excretion, the tiovonin dosage may be decreased or treatment discontinued.
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Urinary excretion of amino acids in normal and cystinuric dogs.
TL;DR: The great variation in urinary cystine excretion suggests that factors other than the excretion of Cystine must be considered as causes of cyStine urolith formation.
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