Cancer-related inflammation.
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Value of the pretreatment albumin to globulin ratio in predicting long-term mortality in breast cancer patients.
Basem Azab,Vijaya Raj Bhatt,Steven Vonfrolio,Rana Bachir,Vladimir Rubinshteyn,Homam Alkaied,Ayman Habeshy,Jignesh Patel,Antonio I. Picon,Scott W. Bloom +9 more
TL;DR: Pretreatment AGR is an independent, significant predictor of long-term mortality in breast cancer patients, even in patients with normal albumin levels.
132
Macrophages are important mediators of either tumor- or inflammation-induced lymphangiogenesis.
TL;DR: Altering of macrophage phenotype and function has a profound effect on the development and progression of inflammation and malignancy, and macrophages depletion for controlling lymphangiogenesis may provide a novel approach for prevention and treatment of lymphatic-associated diseases.
131
ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux
Michelle J. Henderson,Michelle Haber,Antonio Porro,Antonio Porro,Marcia A. Munoz,Nunzio Iraci,Chengyuan Xue,Jayne Murray,Claudia Flemming,Janice Smith,Jamie I. Fletcher,Samuele Gherardi,Chin Kiat Kwek,Amanda J. Russell,Emanuele Valli,Wendy B. London,Allen Buxton,Lesley J. Ashton,Alan C. Sartorelli,Susan L. Cohn,Manfred Schwab,Glenn M. Marshall,Giovanni Perini,Murray D. Norris +23 more
TL;DR: ABCC transporters can affect neuroblastoma biology independently of their role in chemotherapeutic drug efflux, enhancing their potential as targets for therapeutic intervention.
131
The role of inflammation in skin cancer.
TL;DR: In this article, a review focused on compiling available evidence and understanding the role of chronic inflammation in the development of skin cancer was presented, considering the potential role of inflammation in tumor initiation and its major role in promotion/progression, as well as tumor angiogenesis and metastasis; inflammatory pathways may become attractive targets for skin cancer prevention.
131
Value of neutrophil‑to‑lymphocyte ratio for predicting lung cancer prognosis: A meta‑analysis of 7,219 patients
Yu Yu,Lei Qian,Jiuwei Cui +2 more
TL;DR: The results of the present meta-analysis suggested that an elevated pretreatment NLR may be considered as a biomarker for poor prognosis in patients with lung cancer.
References
Inflammation and cancer
Lisa M. Coussens,Zena Werb +1 more
TL;DR: It is now becoming clear that the tumour microenvironment, which is largely orchestrated by inflammatory cells, is an indispensable participant in the neoplastic process, fostering proliferation, survival and migration.
14.4K
Cancer-related inflammation.
TL;DR: The molecular pathways of this cancer-related inflammation are now being unravelled, resulting in the identification of new target molecules that could lead to improved diagnosis and treatment.
Inflammation and cancer: back to Virchow?
TL;DR: A rationale for the use of cytokine and chemokine blockade, and further investigation of non-steroidal anti-inflammatory drugs, in the chemoprevention and treatment of malignant diseases is provided.
7.9K
Involvement of chemokine receptors in breast cancer metastasis.
Anja Müller,Bernhard Homey,Hortensia Soto,Nianfeng Ge,Daniel Catron,Matthew E. Buchanan,Terri McClanahan,Erin Murphy,Wei Yuan,Stephan N. Wagner,Jose Luis Barrera,Alejandro Mohar,Emma Verastegui,Albert Zlotnik +13 more
TL;DR: It is reported that the chemokine receptors CXCR4 and CCR7 are highly expressed in human breast cancer cells, malignant breast tumours and metastases and their respective ligands CXCL12/SDF-1α and CCL21/6Ckine exhibit peak levels of expression in organs representing the first destinations of breast cancer metastasis.
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
Alberto Mantovani,Silvano Sozzani,Silvano Sozzani,Massimo Locati,Paola Allavena,Antonio Sica +5 more
TL;DR: These functionally polarized cells, and similarly oriented or immature dendritic cells present in tumors, have a key role in subversion of adaptive immunity and in inflammatory circuits that promote tumor growth and progression.
5.5K