Calcium ion and muscle contraction.

TL;DR: Ca(2+) regulation of contraction in vertebrate striated muscle is exerted primarily through effects on the thin filament, which regulate strong cross-bridge binding to actin, and the physiological observations of steady-state and transient mechanical behavior are supported.

TL;DR: In this article, the authors discuss the following systemic effects of chronic obstructive pulmonary disease: 1) systemic inflammation; 2) nutritional abnormalities and weight loss; 3) skeletal muscle dysfunction; 4) other potential systemic effects.

TL;DR: Functional alterations of Ca(2+) handling seem to be responsible for the pathophysiological conditions seen in dystrophinopathies, Brody's disease, and malignant hyperthermia, which underline the importance of the affected molecules for correct muscle performance.

TL;DR: The repeated contractions which can be observed in skinned fibres in appropriate concentrations of caffeine, Ca2+ and chelating agent suggest that calcium release is a regenerative process in which calcium itself causes the release of calcium from the reticulum.

TL;DR: Transverse impedance measurements on vertebrate striated muscle over the frequency range 1.5 c/s to 130 kc/s show two dispersions at widely separated frequencies, indicative of two time-dependent impedance elements.

TL;DR: Single fibres were used to achieve a quick change of the external ion concentrations, since a delay would have impeded the analysis of the time course of the transient contractures in twitch fibres.