Cadmium Toxicity and Treatment
TL;DR: Detoxification of cadmium with EDTA and other chelators is possible and has been shown to be therapeutically beneficial in humans and animals when done using established protocols.
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Abstract: Cadmium is a heavy metal of considerable toxicity with destructive impact on most organ systems. It is widely distributed in humans, the chief sources of contamination being cigarette smoke, welding, and contaminated food and beverages. Toxic impacts are discussed and appear to be proportional to body burden of cadmium. Detoxification of cadmium with EDTA and other chelators is possible and has been shown to be therapeutically beneficial in humans and animals when done using established protocols.
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Citations
Cadmium and nickel co-exposure exacerbates genotoxicity and not oxido-inflammatory stress in liver and kidney of rats: Protective role of omega-3 fatty acid.
Solomon E. Owumi,Yusuff O. Olayiwola,Gbenga E. Alao,Michael A. Gbadegesin,Oyeronke A. Odunola +4 more
TL;DR: Results showed that co‐exposure to Cd and Ni aggravated genotoxicity and not oxido‐inflammatory stress in the liver and kidney of rats, and ω‐3FA administration markedly ameliorated the genot toxicity and histological lesions in the co-exposure group.
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Determining lead, cadmium and mercury in cosmetics using sweeping via dynamic chelation by capillary electrophoresis
TL;DR: A small quantity of chelating agents introduced into the capillary could yield 33-, 50- and 100-fold detection improvements for Pb, Cd and Hg, respectively, more sensitive than conventional capillary zone electrophoresis.
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Metabolic effects of long-term cadmium exposure: an overview
TL;DR: The changes in metabolic profiles of humans and rodents under long-term Cd exposure from the perspective of metabolomics are focused on and the relationship between the disturbance of metabolic pathways and the toxic mechanism of Cd is discussed to facilitate the development of reliable metabolic biomarkers for early detection and diagnosis of C d-related diseases.
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Synthesis and application of quantum dots in detection of environmental contaminants in food: A comprehensive review.
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TL;DR: In this article , the types and synthesis methods of QDs with a focus on green synthesis and the research progress on rapid detection of environmental pollutants (e.g., heavy metals, pesticides, and antibiotics) in food are reviewed.
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TL;DR: This chapter provides an overview of the top 10, highest ranking environmental contaminants of concern as identified by the Agency for Toxic Substances and Disease Registry, four priority air pollutants, and seven contaminants of emerging concern.
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References
Composition of the Continental Crust
Roberta L. Rudnick,Shan Gao +1 more
TL;DR: In this paper, the present-day composition of the continental crust, the methods employed to derive these estimates, and the implications of continental crust composition for the formation of the continents, Earth differentiation, and its geochemical inventories are discussed.
The composition of the continental crust
TL;DR: In this paper, a new calculation of the crustal composition is based on the proportions of upper crust (UC) to felsic lower crust (FLC) to mafic lower-crust (MLC) of about 1.6:0.4.
6.1K
Metals, toxicity and oxidative stress.
TL;DR: This review summarizes recent findings in the metal-induced formation of free radicals and the role of oxidative stress in the carcinogenicity and toxicity of metals.
Mercury Toxicity and Treatment: A Review of the Literature
TL;DR: D diagnosis of mercury toxicity can be challenging but can be obtained with reasonable reliability and effective therapies for clinical toxicity have been described.
Cadmium stress: an oxidative challenge
Ann Cuypers,Michelle Plusquin,Tony Remans,Marijke Jozefczak,Els Keunen,Heidi Gielen,Kelly Opdenakker,Ambily Ravindran Nair,Elke Munters,Tom Artois,Tim S. Nawrot,Jaco Vangronsveld,Kelly Smeets +12 more
TL;DR: The current review gives an overview on Cd-induced ROS production and anti-oxidative defense in organisms under different Cd regimes and the C d-induced oxidative challenge is discussed with a focus on damage and signaling as downstream responses.
1K