Journal Article10.1016/0163-7258(91)90014-D
Ca2+ extrusion across plasma membrane and Ca2+ uptake by intracellular stores.
Ludwig Missiaen,Frank Wuytack,Luc Raeymaekers,Humbert De Smed,Guy Droogmans,I Declerck,Rik Casteels +6 more
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TL;DR: The aim of this review is to summarize the various systems that remove Ca2+ from the cytoplasm by summarizing the functional regulation of these systems and the recent progress obtained with molecular-biology techniques, which pointed to the existence of different isoforms of the Ca 2+ pump.
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About: This article is published in Pharmacology & Therapeutics. The article was published on 01 Jan 1991.
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Citations
Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease
Anavaj Sakuntabhai,Victor L. Ruiz-Perez,S. Carter,N. Jacobsen,Susan Burge,Sarah Monk,Martin D. Smith,Colin S. Munro,Michael Conlon O'Donovan,Nicholas John Craddock,Raju Kucherlapati,Jonathan L. Rees,Michael John Owen,G M Lathrop,Anthony P. Monaco,Tom Strachan,Alain Hovnanian +16 more
TL;DR: It is demonstrated that mutations in ATP2A2 cause Darier disease and disclose a role for this pump in a Ca2+-signalling pathway regulating cell-to-cell adhesion and differentiation of the epidermis.
741
Gentamicin and bone morphogenic protein-2 (BMP-2)-delivering heparinized-titanium implant with enhanced antibacterial activity and osteointegration.
TL;DR: Dual drug (antibiotics and osteoinductive protein)-eluting Ti substrates such as GS/BMP-2/Hep-Ti are a promising material for the enhanced osteointegration and implant longevity in orthopedics and dentistry.
168
Structure and function of inositol triphosphate receptors
Colin W. Taylor,Alan Richardson +1 more
TL;DR: The ligand recognition characteristics of Ins(1,4,5) P 3 receptors and their functional properties in their native environment and after purification are discussed, and these properties are related to what is known of the structure of the receptor.
155
Cellular Uptake of Lead Is Activated by Depletion of Intracellular Calcium Stores
TL;DR: In conclusion, Pb2+ crosses the plasma membrane of GH3, C6, and HEK293 cells via channels that are activated by profound depletion of intracellular Ca2+ stores.
139
The plasma membrane calcium pump--a physiological perspective on its regulation.
TL;DR: This review focuses on the physiological role of the plasma membrane Ca(2+)+ Mg(2+)-dependent adenosine triphosphatase (PM Ca( 2+)-ATPase) in cellular signalling and recent work investigating the possible regulation of the PM Ca2+ pump by G proteins and agonists.
135
References
Phospholipid composition modulates the Na+-Ca2+ exchange activity of cardiac sarcolemma in reconstituted vesicles
TL;DR: The results indicate that optimal Na+-Ca2+ exchange activity requires the presence of certain anionic phospholipids, and that the mechanism of action of altered pH on the exchanger appears to be different from other interventions.
Molecular cloning and functional expression of the cardiac sarcolemmal Na(+)-Ca2+ exchanger
TL;DR: Hydropathy analysis suggests that the Na(+)-Ca2+ exchanger of the cardiac sarcolemma can rapidly transport Ca2+ during excitation-contraction coupling and has multiple transmembrane helices, and a small region of the sequence is similar to that of the Na- and K-dependent adenosine triphosphatase.
Cyclic GMP-dependent protein kinase stimulates the plasma membrane Ca2+ pump ATPase of vascular smooth muscle via phosphorylation of a 240-kDa protein.
TL;DR: Results suggest that the phosphorylation of the 240-kDa protein is responsible for stimulation of the plasma membrane Ca2+ pump ATPase by G-kinase.
cDNA cloning, functional expression, and mRNA tissue distribution of a third organellar Ca2+ pump.
TL;DR: The characterization of a rat kidney cDNA that encodes a novel Ca2+-transporting ATPase and that its mRNA is expressed in a broad variety of both muscle and non-muscle tissues are described.
Glucagon-(19-29) exerts a biphasic action on the liver plasma membrane Ca2+ pump which is mediated by G proteins.
Sophie Lotersztajn,Catherine Pavoine,V. Brechler,B. Roche,M. Dufour,Dung Le-Nguyen,Dominique Bataille,Françoise Pecker +7 more
TL;DR: It is concluded that glucagon-(19-29) can exert a biphasic effect on the Ca2+ pump which is mediated by G protein(s) sensitive to cholera toxin.