Journal Article10.1016/0163-7258(91)90014-D
Ca2+ extrusion across plasma membrane and Ca2+ uptake by intracellular stores.
Ludwig Missiaen,Frank Wuytack,Luc Raeymaekers,Humbert De Smed,Guy Droogmans,I Declerck,Rik Casteels +6 more
107
TL;DR: The aim of this review is to summarize the various systems that remove Ca2+ from the cytoplasm by summarizing the functional regulation of these systems and the recent progress obtained with molecular-biology techniques, which pointed to the existence of different isoforms of the Ca 2+ pump.
read more
About: This article is published in Pharmacology & Therapeutics. The article was published on 01 Jan 1991.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease
Anavaj Sakuntabhai,Victor L. Ruiz-Perez,S. Carter,N. Jacobsen,Susan Burge,Sarah Monk,Martin D. Smith,Colin S. Munro,Michael Conlon O'Donovan,Nicholas John Craddock,Raju Kucherlapati,Jonathan L. Rees,Michael John Owen,G M Lathrop,Anthony P. Monaco,Tom Strachan,Alain Hovnanian +16 more
TL;DR: It is demonstrated that mutations in ATP2A2 cause Darier disease and disclose a role for this pump in a Ca2+-signalling pathway regulating cell-to-cell adhesion and differentiation of the epidermis.
741
Gentamicin and bone morphogenic protein-2 (BMP-2)-delivering heparinized-titanium implant with enhanced antibacterial activity and osteointegration.
TL;DR: Dual drug (antibiotics and osteoinductive protein)-eluting Ti substrates such as GS/BMP-2/Hep-Ti are a promising material for the enhanced osteointegration and implant longevity in orthopedics and dentistry.
168
Structure and function of inositol triphosphate receptors
Colin W. Taylor,Alan Richardson +1 more
TL;DR: The ligand recognition characteristics of Ins(1,4,5) P 3 receptors and their functional properties in their native environment and after purification are discussed, and these properties are related to what is known of the structure of the receptor.
155
Cellular Uptake of Lead Is Activated by Depletion of Intracellular Calcium Stores
TL;DR: In conclusion, Pb2+ crosses the plasma membrane of GH3, C6, and HEK293 cells via channels that are activated by profound depletion of intracellular Ca2+ stores.
139
The plasma membrane calcium pump--a physiological perspective on its regulation.
TL;DR: This review focuses on the physiological role of the plasma membrane Ca(2+)+ Mg(2+)-dependent adenosine triphosphatase (PM Ca( 2+)-ATPase) in cellular signalling and recent work investigating the possible regulation of the PM Ca2+ pump by G proteins and agonists.
135
References
Inhibition of Ca2+ transport in mitochondria by selective blockade of membrane mucopolysaccharides by hexamine cobaltichloride
TL;DR: The effect of hexamine cobaltichloride, [Co(NH,),]Cl, (HAC), upon calcium transport and certain other functional parameters of intact rat liver mitochondria and upon the calcium binding by the acid glycoproteid isolated from the inner mitochondri~ membr~e has been investigated.
35
Partial purification of Na+-Ca2+ antiporter from plasma membrane of chick heart.
TL;DR: The pronase treatment was very useful for obtaining reconstituted liposomes containing highly enriched Na+-Ca2+ antiporters which were functionally intact and the fundamental properties of Nai+-dependent Ca2+ uptake in purified proteoliposomes such as Km for Ca2+, were nearly equal to those in membrane vesicles and crude proteolipsomes.
34
Release of Ca2+ by inositol 1,4,5-trisphosphate in platelet membrane vesicles is not dependent on cyclic AMP-dependent protein kinase.
TL;DR: In contrast with previous reports, it was found that membrane-protein phosphorylation by the catalytic subunit (CS) of cyclic AMP-dependent protein kinase had no effect on Ca2+ uptake into platelet membrane vesicles or on subsequentCa2+ release by inositol 1,4,5-trisphosphate (IP3).
Optical measurements of Na-Ca-K exchange currents in intact outer segments isolated from bovine retinal rods.
TL;DR: It is demonstrated that Na-Ca-K exchange current in bovine ROS can be measured with the dye neutral red and dual-wavelength spectrophotometry and competitive interactions between Ca2+ and Na+ ions on the exchanger protein are described.
33
Measurement of mitochondrial and non-mitochondrial Ca2+ in isolated intact hepatocytes: a critical re-evaluation of the use of mitochondrial inhibitors.
TL;DR: Findings demonstrate that, in freshly isolated hepatocytes, FCCP specifically releases Ca2+ from mitochondrial stores without significantly affecting active Ca2+, and can be used to release and quantitate mitochondrial Ca 2+ in liver cells.
33