Journal Article10.1016/0163-7258(91)90014-D
Ca2+ extrusion across plasma membrane and Ca2+ uptake by intracellular stores.
Ludwig Missiaen,Frank Wuytack,Luc Raeymaekers,Humbert De Smed,Guy Droogmans,I Declerck,Rik Casteels +6 more
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TL;DR: The aim of this review is to summarize the various systems that remove Ca2+ from the cytoplasm by summarizing the functional regulation of these systems and the recent progress obtained with molecular-biology techniques, which pointed to the existence of different isoforms of the Ca 2+ pump.
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About: This article is published in Pharmacology & Therapeutics. The article was published on 01 Jan 1991.
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Citations
Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease
Anavaj Sakuntabhai,Victor L. Ruiz-Perez,S. Carter,N. Jacobsen,Susan Burge,Sarah Monk,Martin D. Smith,Colin S. Munro,Michael Conlon O'Donovan,Nicholas John Craddock,Raju Kucherlapati,Jonathan L. Rees,Michael John Owen,G M Lathrop,Anthony P. Monaco,Tom Strachan,Alain Hovnanian +16 more
TL;DR: It is demonstrated that mutations in ATP2A2 cause Darier disease and disclose a role for this pump in a Ca2+-signalling pathway regulating cell-to-cell adhesion and differentiation of the epidermis.
741
Gentamicin and bone morphogenic protein-2 (BMP-2)-delivering heparinized-titanium implant with enhanced antibacterial activity and osteointegration.
TL;DR: Dual drug (antibiotics and osteoinductive protein)-eluting Ti substrates such as GS/BMP-2/Hep-Ti are a promising material for the enhanced osteointegration and implant longevity in orthopedics and dentistry.
168
Structure and function of inositol triphosphate receptors
Colin W. Taylor,Alan Richardson +1 more
TL;DR: The ligand recognition characteristics of Ins(1,4,5) P 3 receptors and their functional properties in their native environment and after purification are discussed, and these properties are related to what is known of the structure of the receptor.
155
Cellular Uptake of Lead Is Activated by Depletion of Intracellular Calcium Stores
TL;DR: In conclusion, Pb2+ crosses the plasma membrane of GH3, C6, and HEK293 cells via channels that are activated by profound depletion of intracellular Ca2+ stores.
139
The plasma membrane calcium pump--a physiological perspective on its regulation.
TL;DR: This review focuses on the physiological role of the plasma membrane Ca(2+)+ Mg(2+)-dependent adenosine triphosphatase (PM Ca( 2+)-ATPase) in cellular signalling and recent work investigating the possible regulation of the PM Ca2+ pump by G proteins and agonists.
135
References
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TL;DR: Glucose 6-phosphate is proposed to provide a regulatory link between glucose metabolism and intracellular Ca2+ regulation by augmentingCa2+ sequestered in the ER as well as attenuating IP3-induced Ca2-induced release.
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Hormonal regulation of (Ca2+ + Mg2+)ATPase activity in canine renal basolateral membrane.
TL;DR: The data suggest that insulin and PTH have a specific stimulatory effect on (Ca2+ + Mg2+)ATPase activity in canine kidney proximal tubular BLM, and suggests that these hormones mediate their cellular effects in part by changes in cellular calcium homeostasis.
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Active accumulation of sr2+ by rat-liver mitochondria. ii. competition between ca2+ and sr2+.
TL;DR: Ca2+ inhibits the respiration-linked accumulation of Sr2+ in a competitive manner and the release of both Sr2- and Ca2+ from “loaded” mitochondria is promoted by 2,4-dinitrophenol.
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Cooperative calcium binding and calmodulin regulation in the calcium-dependent adenosine triphosphatase purified from the erythrocyte membrane
TL;DR: Erythrocyte membrane Ca2+‐ATPase Calmodulin Purified Ca2‐atPase Intrinsic fluorescence Cooperativity
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Solubilization and reconstitution of the Na+/Ca2+ exchanger of cardiac sarcolemma. Properties of the reconstituted system and tentative identification of the protein(s) responsible for the exchange activity.
L Soldati,S Longoni,E Carafoli +2 more
TL;DR: The fractionation scheme used has shown that the exchange activity correlated best with a 33-kDa protein present in the fractionated extract, which may represent the Na+/Ca2+ exchanger of cardiac sarcolemma.
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