Journal Article10.1016/J.JORGANCHEM.2018.02.023
Buchwald-Hartwig reaction: An overview
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TL;DR: In this article, the Buchwald-Hartwig amination reaction has attracted much attention in recent years, especially applied for construction of various heterocyclic systems, and the applications of this name reaction as an important C-N cross-coupling reaction applied to the total synthesis of natural products.
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About: This article is published in Journal of Organometallic Chemistry. The article was published on 15 Apr 2018. The article focuses on the topics: Amination & Name reaction.
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Citations
The Buchwald–Hartwig Amination After 25 Years
TL;DR: This Minireview summarizes the evolution of this cross-coupling reaction over the course of the past 25 years and illustrates some of the most recent applications of this well-established methodology.
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Bisphosphines: A Prominent Ancillary Ligand Class for Application in Nickel-Catalyzed C–N Cross-Coupling
TL;DR: The Ni-catalyzed Csp2-N cross-coupling of NH substrates and (hetero)aryl (pseudo) halides for the synthesis of anilines is in the midst of a resurgence as mentioned in this paper.
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The key role of R–NHC coupling (R = C, H, heteroatom) and M–NHC bond cleavage in the evolution of M/NHC complexes and formation of catalytically active species
Victor M. Chernyshev,Ekaterina A. Denisova,Dmitry B. Eremin,Dmitry B. Eremin,Valentine P. Ananikov +4 more
TL;DR: Main types of the M–NHC bond transformations and their impact on activity and stability of M/NHC catalytic systems are considered.
A Highly Active Ylide-Functionalized Phosphine for Palladium-Catalyzed Aminations of Aryl Chlorides
Philip Weber,Thorsten Scherpf,Ilja Rodstein,Dominik Lichte,Lennart T. Scharf,Lukas J. Gooßen,Viktoria H. Gessner +6 more
TL;DR: Benchmark studies showed that YPhos-Pd complexes are superior to the best-known phosphine ligands in room-temperature aminations of aryl chlorides.
104
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