Journal Article10.1016/J.TCB.2008.08.007
Breaching the basement membrane: who, when and how?
R. Grant Rowe,Stephen J. Weiss +1 more
466
TL;DR: New data indicate that protease-dependent transmigration is largely reliant on a group of membrane-anchored metalloenzymes, termed the membrane-type matrix metalloproteinases, which irreversibly remodel BM structure.
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About: This article is published in Trends in Cell Biology. The article was published on 01 Nov 2008.
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Citations
Derivation and Application of Effective Interface Conditions for Continuum Mechanical Models of Cell Invasion through Thin Membranes
TL;DR: In this article, the authors consider a continuum mechanical model of cell invasion through thin membranes, which consists of a transmission problem for cell volume fraction complemented with continuity of stresses and stability of stresses.
Basement membrane invasion assays: native basement membrane and chemoinvasion assay.
Marie Schoumacher,Marie Schoumacher,Alexandros Glentis,Vasily Gurchenkov,Danijela Matic Vignjevic +4 more
TL;DR: Two complementary invasion assays are described, based on BM isolated from rat or mouse mesentery and Matrigel-based chemoinvasion assay, for studying invadopodia's molecular composition and organization at the subcellular level.
19
Peroxidasin: tying the collagen-sulfilimine knot.
TL;DR: Type IV collagen, a major constituent of basement membranes, contains an unusual intermolecular sulfilimine crosslink whose route of biosynthesis has remained undefined, and an oxidative triad consisting of peroxidasin, H( 2)O(2) and halide is now shown to drive sulfILimine generation in vivo.
18
The SWI/SNF chromatin remodeling assemblies BAF and PBAF differentially regulate cell cycle exit and cellular invasion in vivo
Jayson J. Smith,Xiao Y,Parsan N,Martinez Maq,Moore Feq,Nicholas J. Palmisano,Kohrman Aq,Reyes Mcd,Rebecca C. Adikes,Taylor N. Medwig-Kinney,Liu S,Bracht Sa,Bracht Sa,Wan Zhang,Wen K,Paschalis Kratsios,David Q. Matus +16 more
TL;DR: It is demonstrated that the SWI/SNF ATP-dependent chromatin remodeling complex is a critical regulator of AC invasion, with pleiotropic effects on both G0 cell cycle arrest and activation of invasive machinery.
18
Biomaterial strategies to replicate gynecological tissue
TL;DR: A general overview of the biology and components of the major tissues that make up the female reproductive system as well as a comprehensive survey of the different biomaterials that have been chosen to build in vitro models of these tissues are provided.
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