Journal Article10.1016/J.INTIMP.2005.10.005
Botanical polysaccharides: macrophage immunomodulation and therapeutic potential.
Igor A. Schepetkin,Mark T. Quinn +1 more
1.1K
TL;DR: The evaluation of botanical polysaccharide isolated from a wide array of different species of flora provides a unique opportunity for the discovery of novel therapeutic agents and adjuvants that exhibit beneficial immunomodulatory properties.
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About: This article is published in International Immunopharmacology. The article was published on 01 Mar 2006.
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Citations
Evaluation of radicals scavenging, immunity-modulatory and antitumor activities of longan polysaccharides with ultrasonic extraction on in S180 tumor mice models.
TL;DR: UELP showed excellent scavenging activity on the hydroxyl radicals and a,a-diphenyl-1-picrylhydrazyl (DPPH) radicals, and obtained the almost complete scavenging effect, and maximum inhibition rate was obtained at medium-dose and low-dose (200 and 100mg/kg).
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Structure characterization of a novel polysaccharide from Hericium erinaceus fruiting bodies and its immunomodulatory activities.
TL;DR: The immunomodulatory assay indicated that HEP-S could significantly enhance the pinocytic and phagocytic capacity and promote the secretion of nitric oxide and pro-inflammatory cytokines by activating the corresponding mRNA and protein expression in RAW 2647 cells involving a toll-like receptor 2 membrane receptor.
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Anti-colon-cancer effects of polysaccharides: A mini-review of the mechanisms.
Xiaolong Ji,Qiang Peng,Min Wang +2 more
TL;DR: A comprehensive review of the literature was undertaken to summarize the studies reported in 2012-2017, and the apoptogenic mechanisms of polysaccharide-rich extracts in colon cancer tumor cells were assessed.
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Role of phytochemicals as immunomodulatory agents: A review
TL;DR: The present review focused on the immune-modulating activity of various phytochemicals such as alkaloids, polysaccharides, lectins, glycosides, phenolic compounds, flavonoids, anthocyanins, tannins, saponins, terpenoids, sterols and also explains the role of antioxidants as immune- modulators.
A polysaccharide isolated from the fruits of Physalis alkekengi L. induces RAW264.7 macrophages activation via TLR2 and TLR4-mediated MAPK and NF-κB signaling pathways
TL;DR: It is illustrated that PPSB was capable of activating the RAW264.7 cells via MAPKs and NF-κB signaling mediated by TLR2 and TLR4.
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