Open AccessBook
Biotransformations in Organic Chemistry
Kurt Faber
- 01 Jan 1992
TL;DR: This professional referencebook on Biotransformations in organic Chemistry is aimed at graduate students in Organic Chemistry and Biotechnology, scientists and professionals who want to use the powerful synthetic tool of enzymes for modern preparative organic chemistry.
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Abstract: The use of biocatalysts as enzymes and/or whole cells, offers a remarkable arsenal of highly selective transformations in preparative organic chemistry. A large number of synthetically useful reactions can be catalysed by enzymes in a highly selective manner. This book pinpoints the chemo-, regio- and stereoselective transformations which have been shown to be most useful as an alternative to the already existing methods for stereoselective synthesis. The types of reaction covered inter alia are: hydrolysis-condensation, redox-reactions, addition-elimination, carbon-carbon bond formation, halogenation, etc. Special techniques, such as enzyme-immobilization and the use of biocatalysts in organic solvents are introduced to the newcomer. This is the first approach to provide a condensed introduction into this field written from the viewpoint of an organic chemist. This professional referencebook on Biotransformations in Organic Chemistry is aimed at graduate students in Organic Chemistry and Biotechnology, scientists and professionals who want to use the powerful synthetic tool of enzymes for modern preparative organic chemistry.
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Citations
Asymmetric Reduction of Heteroaryl Methyl Ketones Using Daucus carota
TL;DR: The present methodology demonstrates promising and alternative green route in the synthesis secondary chiral alcohols of biologically importance in a simple, inexpensive and eco-friendly process.
Chemical transformations of renewable lubricant feedstocks
Jan C.J. Bart,Emanuele Gucciardi,Stefano Cavallaro +2 more
- 01 Jan 2013
TL;DR: In this article, the carboxyl moiety of fatty acid chains has been considered as an important step for improving the performance of renewable feedstocks (vegetable oils, starches) as lubricant base stocks.
13
Enzymatic reaction in a vesicular microreactor: peptaibol-facilitated substrate transport.
T. N. Kropacheva,Jan Raap +1 more
TL;DR: The rate of the extra‐ or intravesicular enzymatic reaction was found to be controlled by substrate diffusion through the lipid bilayer, and an up to seven‐fold increase in reaction rate was observed in the presence of either ALM or ZER.
13
Lipase-catalyzed dynamic hydrolytic resolution of (R,S)-2,2,2-trifluoroethyl α-chlorophenyl acetate in water-saturated isooctane
TL;DR: In this article, an enantiomeric ratio of 33.6 was estimated and employed for the modeling of time-course conversions of both substrates by considering product inhibition and enzyme deactivation effects.
13
References
•Book
Biocatalysis in Organic Media
L.E.S. Brink,Johannes Tramper,K. Ch. A. M. Luyben,K. van 't Riet +3 more
- 01 Jun 1987
TL;DR: The epoxidation of alkenes in water/solvent two-phase systems is discussed to give an example of the scope of biotechnological processes that is obtained by using organic media.
596
Enzymes in organic synthesis-29 : Preparations of enantiomerically pure cis -2,3- and 2,4-dimethyl lactones via horse liver alcohol dehydrogenase-catalyzed oxidations☆☆☆
TL;DR: In this paper, the broad applicability of horse liver alcohol dehydrogenase-catalyzed oxidations of meso-diols as a route to chiral lactones of asymmetric synthetic value is described.
325
Biocatalysis in agricultural biotechnology
John R. Whitaker,Philip E. Sonnet +1 more
- 01 Jan 1989
TL;DR: That's it, a book to wait for in this month for releasing this book biocatalysis in agricultural biotechnology; you may not be able to get in some stress, so don't go around and seek fro the book until you really get it.
185
•Book
Biocatalysis: From Discovery to Application
Wolf-Dieter Fessner
- 15 Mar 2000
TL;DR: The present work focused on the development of biocatalytic Approaches for the Synthesis of Enantiopure Epoxides with a focus on the components of the E. coli Oligosaccharides.
155