Open AccessBook
Biotransformations in Organic Chemistry
Kurt Faber
- 01 Jan 1992
TL;DR: This professional referencebook on Biotransformations in organic Chemistry is aimed at graduate students in Organic Chemistry and Biotechnology, scientists and professionals who want to use the powerful synthetic tool of enzymes for modern preparative organic chemistry.
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Abstract: The use of biocatalysts as enzymes and/or whole cells, offers a remarkable arsenal of highly selective transformations in preparative organic chemistry. A large number of synthetically useful reactions can be catalysed by enzymes in a highly selective manner. This book pinpoints the chemo-, regio- and stereoselective transformations which have been shown to be most useful as an alternative to the already existing methods for stereoselective synthesis. The types of reaction covered inter alia are: hydrolysis-condensation, redox-reactions, addition-elimination, carbon-carbon bond formation, halogenation, etc. Special techniques, such as enzyme-immobilization and the use of biocatalysts in organic solvents are introduced to the newcomer. This is the first approach to provide a condensed introduction into this field written from the viewpoint of an organic chemist. This professional referencebook on Biotransformations in Organic Chemistry is aimed at graduate students in Organic Chemistry and Biotechnology, scientists and professionals who want to use the powerful synthetic tool of enzymes for modern preparative organic chemistry.
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Citations
Stereoselectivity of the generation of 3-mercaptohexanal and 3-mercaptohexanol by lipase-catalyzed hydrolysis of 3-acetylthioesters.
TL;DR: The enantioselectivity of the generation of 3-MERcaptohexanal and 3-mercapto hexanol, two potent sulfur-containing aroma compounds, by lipase-catalyzed hydrolysis of the corresponding 3-acetylthioesters was investigated.
22
Cascade approach for synthesis of R-1-phenyl ethyl acetate from acetophenone: Effect of support
Päivi Mäki-Arvela,Serap Sahin,Narendra Kumar,Teemu Heikkilä,Vesa-Pekka Lehto,Tapio Salmi,Dmitry Yu. Murzin +6 more
TL;DR: In this paper, the effect of support acidity was systematically investigated by using two mesoporous Pd-H-MCM-41 and Pd−SiO2 catalysts as hydrogenation catalysts.
22
The production of Pseudomonas putida for the hydroxylation of toluene to its cis-glycol
TL;DR: A constitutive blocked mutant of Pseudomonas putida was grown in a 2.5-l fermentor on a mineral salts medium and the maximum toluene dioxygenase specific activity was obtained over the last 6 h of the fermentation when the pH was fully controlled.
22
Lipase-mediated dynamic kinetic resolution (DKR) of secondary alcohols in the presence of zeolite using an ionic liquid solvent system
Ken-ichi Shimomura,Hiroyuki Harami,Yui Matsubara,Toshiki Nokami,Naonobu Katada,Toshiyuki Itoh +5 more
TL;DR: In this article, the transition metal free dynamic kinetic resolution (DKR) of 1-phenyethanol and 2,3-dihydro-1H-inden-1-ol has been accomplished by the combination of Candida antarctica lipase (CAL-B) and zeolite using vinyl octanoate or p-chlorophenyl pentanoate as acyl donor in a mixed solvent system of ionic liquid and hexane in the presence of 1.0
22
Studies on enzymatic synthesis of chiral non-racemic 3-arylglutaric acid monoesters
TL;DR: In this article, the enantioselective desymmetrization of various 3-arylglutaric anhydrides with alcohols in organic media has been studied.
22
References
•Book
Biocatalysis in Organic Media
L.E.S. Brink,Johannes Tramper,K. Ch. A. M. Luyben,K. van 't Riet +3 more
- 01 Jun 1987
TL;DR: The epoxidation of alkenes in water/solvent two-phase systems is discussed to give an example of the scope of biotechnological processes that is obtained by using organic media.
596
Enzymes in organic synthesis-29 : Preparations of enantiomerically pure cis -2,3- and 2,4-dimethyl lactones via horse liver alcohol dehydrogenase-catalyzed oxidations☆☆☆
TL;DR: In this paper, the broad applicability of horse liver alcohol dehydrogenase-catalyzed oxidations of meso-diols as a route to chiral lactones of asymmetric synthetic value is described.
325
Biocatalysis in agricultural biotechnology
John R. Whitaker,Philip E. Sonnet +1 more
- 01 Jan 1989
TL;DR: That's it, a book to wait for in this month for releasing this book biocatalysis in agricultural biotechnology; you may not be able to get in some stress, so don't go around and seek fro the book until you really get it.
185
•Book
Biocatalysis: From Discovery to Application
Wolf-Dieter Fessner
- 15 Mar 2000
TL;DR: The present work focused on the development of biocatalytic Approaches for the Synthesis of Enantiopure Epoxides with a focus on the components of the E. coli Oligosaccharides.
155