Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective.
TL;DR: The affective neuroethological perspective presented here views the ML-DA system in terms of its ability to activate an instinctual emotional appetitive state (SEEKING) evolved to induce organisms to search for all varieties of life-supporting stimuli and to avoid harms.
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About: This article is published in Brain Research Reviews. The article was published on 01 Dec 2007. and is currently open access. The article focuses on the topics: Associative learning & Incentive salience.
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The basic emotional circuits of mammalian brains: do animals have affective lives?
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Opponency Revisited: Competition and Cooperation Between Dopamine and Serotonin
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References
Dopamine Replacement Therapy Reverses Abnormal Synchronization of Pallidal Neurons in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Primate Model of Parkinsonism
TL;DR: Changes in both pallidal discharge rates and synchronization are correlated with the clinical manifestations of parkinsonism and its pharmacological treatment.
The neurobiology of addiction.
TL;DR: These findings are particularly timely, as law‐ and policymakers are tasked to reverse the ongoing opioid epidemic, as more states legalize marijuana, as new products including electronic cigarettes and newly designed abused substances enter the legal and illegal markets, and as “deaths of despair” from alcohol and drug misuse continue.
185
Molecular genetics support Gray's personality theory: the interaction of COMT and DRD2 polymorphisms predicts the behavioural approach system
TL;DR: The present study provides the first direct molecular genetics support for Gray's Reinforcement Sensitivity Theory (RST), which is one of the most influential biologically oriented personality theories.
180
Dopamine, uncertainty and TD learning.
TL;DR: It is shown that when averaging the non-stationary prediction errors across trials, a ramping in the activity of the dopamine neurons should be apparent, whose magnitude is dependent on the learning rate.
Understanding Addictive Vulnerability: An Evolving Psychodynamic Perspective
E. J. Khantzian
- 01 Jan 2003
TL;DR: In contrast to early psychoanalytic theory, which stressed pleasurable/aggressive drives and the symbolic meaning of drugs to explain their appeal, a modern psychodynamic perspective of substance-use disorders (SUDs) places greater emphasis on intolerable painful or confusing affects that make addictive drugs compelling.
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