Behavioral and Neural Signatures of Working Memory in Childhood.
Monica D. Rosenberg,Monica D. Rosenberg,Steven A. Martinez,Kristina M. Rapuano,May I. Conley,Alexandra O. Cohen,M. Daniela Cornejo,M. Daniela Cornejo,Donald J. Hagler,Wesley J. Meredith,Kevin M. Anderson,Tor D. Wager,Tor D. Wager,Eric Feczko,Eric Earl,Damien A. Fair,M Deanna,Richard Watts,B. J. Casey +18 more
TL;DR: Analysis of data from over 11,500 9- to 10-year-olds enrolled in the Adolescent Brain Cognitive Development Study establishes relationships between working memory, other cognitive abilities, and frontoparietal brain activity during a working memory challenge, but not during other cognitive challenges.
read more
Abstract: Working memory function changes across development and varies across individuals. The patterns of behavior and brain function that track individual differences in working memory during human development, however, are not well understood. Here, we establish associations between working memory, other cognitive abilities, and functional MRI (fMRI) activation in data from over 11,500 9- to 10-year-old children (both sexes) enrolled in the Adolescent Brain Cognitive Development (ABCD) Study, an ongoing longitudinal study in the United States. Behavioral analyses reveal robust relationships between working memory, short-term memory, language skills, and fluid intelligence. Analyses relating out-of-scanner working memory performance to memory-related fMRI activation in an emotional n-back task demonstrate that frontoparietal activity during a working memory challenge indexes working memory performance. This relationship is domain specific, such that fMRI activation related to emotion processing during the emotional n-back task, inhibitory control during a stop-signal task (SST), and reward processing during a monetary incentive delay (MID) task does not track memory abilities. Together, these results inform our understanding of individual differences in working memory in childhood and lay the groundwork for characterizing the ways in which they change across adolescence.SIGNIFICANCE STATEMENT Working memory is a foundational cognitive ability that changes over time and varies across individuals. Here, we analyze data from over 11,500 9- to 10-year-olds to establish relationships between working memory, other cognitive abilities, and frontoparietal brain activity during a working memory challenge, but not during other cognitive challenges. Our results lay the groundwork for assessing longitudinal changes in working memory and predicting later academic and other real-world outcomes.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Reproducible brain-wide association studies require thousands of individuals
Scott Marek,Brenden Tervo-Clemmens,Finnegan J. Calabro,David F. Montez,Benjamin P Kay,Alexander S. Hatoum,Meghan Rose Donohue,Will Foran,Ryland L. Miller,Timothy Hendrickson,Stephen M. Malone,Sridhar Kandala,Eric Feczko,Oscar Miranda-Dominguez,Alice M. Graham,Eric Earl,Anders Perrone,Michaela Cordova,Olivia Doyle,Lucille A. Moore,Gregory Mark Conan,Johnny Uriarte,Katherine Allene Snider,Benjamin J. Lynch,James C. Wilgenbusch,Thomas Pengo,Angela Tam,Jianzhong Chen,Dillan J. Newbold,Annie Zheng,Nicole A Seider,Andrew N. Van,Athanasia Metoki,Roselyne Chauvin,Timothy O. Laumann,Deanna J. Greene,Steven E. Petersen,Hugh Garavan,Wesley K. Thompson,Thomas E. Nichols,B.T. Thomas Yeo,Deanna M. Barch,Beatriz Luna,Damien A. Fair,Nico U.F. Dosenbach +44 more
TL;DR: In this article , the authors used three of the largest neuroimaging datasets currently available, with a total sample size of around 50,000 individuals, to quantify brain-wide association studies effect sizes and reproducibility as a function of sample size.
Activity in the fronto-parietal multiple-demand network is robustly associated with individual differences in working memory and fluid intelligence.
Moataz Assem,Idan Blank,Zachary Mineroff,Ahmet Ademoglu,Evelina Fedorenko,Evelina Fedorenko,Evelina Fedorenko +6 more
TL;DR: It is demonstrated that a core component of individual differences variance in executive abilities and fluid intelligence is selectively and robustly positively associated with the level of activity in the MD network, a result that aligns well with lesion studies.
76
Baseline brain function in the preadolescents of the ABCD Study.
Bader Chaarani,Sage Hahn,Nicholas Allgaier,Shana Adise,Max M. Owens,Anthony C. Juliano,D K Yuan,Hannah Loso,A Ivanciu,Matthew D. Albaugh,Julie A. Dumas,Scott Mackey,Jennifer Laurent,Masha Y. Ivanova,Donald J. Hagler,M D Cornejo,Sean N. Hatton,Arpana Agrawal,Laika D. Aguinaldo,L Ahonen,Will M. Aklin,Andrey P. Anokhin,Judith A. Arroyo,Shelli Avenevoli,D Babcock,Kara S. Bagot,Fiona C. Baker,Marie T. Banich,Hauke Bartsch,Arielle R. Baskin-Sommers,James M. Bjork,D Blachman-Demner,M Bloch,Ryan Bogdan,Susan Y. Bookheimer,Florence J. Breslin,S.A. Brown,Finnegan J. Calabro,Calhoun Vd,Calhoun Vd,B. J. Casey,Linda Chang,Duncan B. Clark,Christine C. Cloak,Robert Todd Constable,K Constable,Robin C. Corley,Linda B. Cottler,Stefany Coxe,Rada K. Dagher,Anders M. Dale,Mirella Dapretto,Rebecca DelCarmen-Wiggins,Anthony Steven Dick,Elizabeth K. Do,Nico U.F. Dosenbach,Gayathri J. Dowling,Sarah Edwards,Thomas Ernst,Damien A. Fair,Chun Chieh Fan,Eric Feczko,Sarah W. Feldstein-Ewing,Paul Florsheim,John J. Foxe,Edward G. Freedman,Naomi P. Friedman,S Friedman-Hill,Bernard F. Fuemmeler,Adriana Galván,Dylan G. Gee,Jay N. Giedd,Meyer D. Glantz,Paul E.A. Glaser,Job G. Godino,Marybel Robledo Gonzalez,Raul Gonzalez,Steven Grant,Kevin M. Gray,Frank Haist,Michael P. Harms,Samuel W. Hawes,A C Heath,Steven G. Heeringa,Mary M. Heitzeg,Robert Hermosillo,Megan M. Herting,John M. Hettema,John K. Hewitt,Charles J. Heyser,Elizabeth A. Hoffman,Katia D. Howlett,Rebekah S. Huber,Marilyn A. Huestis,Luke W. Hyde,William G. Iacono,Maria Alejandra Infante,Okan Irfanoglu,Amal Isaiah,S Iyengar,Joanna Jacobus,R James,Beda Jean-Francois,Terry L. Jernigan,Nicole R. Karcher,A Kaufman,B Kelley,B Kit,A Ksinan,Joshua M. Kuperman,Angela R. Laird,Christine L. Larson,Kimberly H. LeBlanc,C Lessov-Schlagger,N Lever,David A. Lewis,Krista M. Lisdahl,A R Little,Marsha F. Lopez,Monica Luciana,Beatriz Luna,P. A. F. Madden,Hermine H. Maes,Carolina Makowski,Andrew T Marshall,Michael J. Mason,John A. Matochik,Bruce D. McCandliss,Erin McGlade,I Montoya,G Morgan,Amanda Sheffield Morris,C Mulford,P Murray,Bonnie J. Nagel,Michael C. Neale,Gretchen N. Neigh,Andrew S. Nencka,Antonio Noronha,Sara Jo Nixon,Clare E. Palmer,Vani Pariyadath,Martin P. Paulus,William E. Pelham,D Pfefferbaum,Carlo Pierpaoli,Andrew P. Prescot,Devin Prouty,Leon I. Puttler,N Rajapaske,Kristina M. Rapuano,Gloria Reeves,Perry F. Renshaw,Michael C. Riedel,P Rojas,M. De La Rosa,Monica D. Rosenberg,M J Ross,Mariana Sanchez,Claudiu Schirda,D Schloesser,John E. Schulenberg,Kenneth J. Sher,Chandni Sheth,Paul D. Shilling,W K Simmons,Elizabeth R. Sowell,Nicole Speer,M Spittel,Lindsay M. Squeglia,C Sripada,Joel L. Steinberg,C Striley,Matthew T. Sutherland,Jody Tanabe,Susan F. Tapert,Thompson Wk,Rachel L. Tomko,Kristina A. Uban,Scott I. Vrieze,Natasha E. Wade,Richard Watts,Susan R.B. Weiss,B A Wiens,O D Williams,A Wilbur,D Wing,Dana L. Wolff-Hughes,R Yang,Deborah A. Yurgelun-Todd,Robert A. Zucker,Alexandra Potter,Hugh Garavan +192 more
TL;DR: In the Adolescent Brain Cognitive Development (ABCD) study as discussed by the authors, the authors report activation patterns from functional MRI (fMRI) tasks completed at baseline, which were designed to measure cognitive impulse control with a stop signal task (SST; N = 5,547), reward anticipation and receipt with a monetary incentive delay (MID) task (N = 6,657), and working memory and emotion reactivity with an emotional N-back (EN-back) task.
76
Emotional Neuroscience and Learning. An Overview
TL;DR: In this paper , the effects of emotion on cognitive function, memory, and learning processes were reviewed using electronic databases (PubMed and Scopus) to emphasize the most recent literature, articles published within the last fifteen years.
39
Prenatal cannabis exposure predicts attention problems, without changes on fMRI in adolescents.
Leigh-Anne Cioffredi,Hillary Anderson,Hannah Loso,James East,Philip Nguyen,Hugh Garavan,Alexandra Potter +6 more
TL;DR: The authors found that prenatal cannabis exposure (PCE) would be associated with increased attention problems and altered neurocognition in young adolescents and found that participants with PCE had significantly higher attention problems, internalizing, externalizing, and total problem scores.
22
References
Control of goal-directed and stimulus-driven attention in the brain
TL;DR: Evidence for partially segregated networks of brain areas that carry out different attentional functions is reviewed, finding that one system is involved in preparing and applying goal-directed selection for stimuli and responses, and the other is specialized for the detection of behaviourally relevant stimuli.
12.7K
The organization of the human cerebral cortex estimated by intrinsic functional connectivity
B.T. Thomas Yeo,Fenna M. Krienen,Jorge Sepulcre,Jorge Sepulcre,Mert R. Sabuncu,Mert R. Sabuncu,Danial Lashkari,Marisa O. Hollinshead,Marisa O. Hollinshead,Joshua L. Roffman,Jordan W. Smoller,Lilla Zöllei,Jonathan R. Polimeni,Bruce Fischl,Bruce Fischl,Hesheng Liu,Randy L. Buckner +16 more
TL;DR: In this paper, the organization of networks in the human cerebrum was explored using resting-state functional connectivity MRI data from 1,000 subjects and a clustering approach was employed to identify and replicate networks of functionally coupled regions across the cerebral cortex.
7.4K
Effects of noise letters upon the identification of a target letter in a nonsearch task
TL;DR: In this paper, a 1-sec tachistoscopic exposure, Ss responded with a right or left leverpress to a single target letter from the sets H and K or S and C. The target always appeared directly above the fixation cross.
Functional network organization of the human brain
Jonathan D. Power,Alexander L. Cohen,Steven M. Nelson,Gagan S. Wig,Kelly Anne Barnes,Jessica A. Church,Alecia C. Vogel,Timothy O. Laumann,F.M. Miezin,Bradley L. Schlaggar,Steven E. Petersen +10 more
TL;DR: In this article, the authors studied functional brain organization in healthy adults using resting state functional connectivity MRI and proposed two novel brain wide graphs, one of 264 putative functional areas, the other a modification of voxelwise networks that eliminates potentially artificial short-distance relationships.
4.2K
Normality Tests for Statistical Analysis: A Guide for Non-Statisticians
Asghar Ghasemi,Saleh Zahediasl +1 more
TL;DR: The aim of this commentary is to overview checking for normality in statistical analysis using SPSS.
3.8K
Related Papers (5)
B. J. Casey,B. J. Casey,Tariq Cannonier,May I. Conley,May I. Conley,Alexandra O. Cohen,M Deanna,Mary M. Heitzeg,Mary E. Soules,Theresa Teslovich,Danielle V. Dellarco,Hugh Garavan,Catherine Orr,Tor D. Wager,Marie T. Banich,Nicole Speer,Matthew T. Sutherland,Michael C. Riedel,Anthony Steven Dick,James M. Bjork,Kathleen M. Thomas,Bader Chaarani,Margie Hernandez Mejia,Donald J. Hagler,M. Daniela Cornejo,Chelsea S. Sicat,Michael P. Harms,Nico U.F. Dosenbach,Monica D. Rosenberg,Eric Earl,Hauke Bartsch,Richard Watts,Jonathan R. Polimeni,Joshua M. Kuperman,Damien A. Fair,Anders M. Dale +35 more