Book Chapter10.1007/978-1-4684-2088-3_12
Basic Concepts in the Effects of Mass Transfer on Immobilized Enzyme Kinetics
Bruce K. Hamilton,Colin R. Gardner,Clark K. Colton +2 more
- 01 Jan 1974
- pp 205-224
11
TL;DR: With adequate care, it is then possible to interpret meaningfully values of commonly reported immobilized enzyme kinetic parameters, such as the “apparent Michaelis constant,” even if severe mass transfer effects are present when rate data are obtained.
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Abstract: The observed kinetics of immobilized enzymes can often be influenced by mass transfer effects. To ensure straight-forward and useful analysis of data, these influences should be anticipated at the early stages of design and execution of kinetic experiments. With adequate care, it is then possible to interpret meaningfully values of commonly reported immobilized enzyme kinetic parameters, such as the “apparent Michaelis constant,” even if severe mass transfer effects are present when rate data are obtained.
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Citations
Beta‐galactosidase technology: A solution to the lactose problem
TL;DR: The enzyme can be used on a semi-continuous or continuous basis in bioreactors for large-scale reduction of lactose content of milk and other dairy products, and production of sweetener concentrates and food syrups.
166
Immobilized Biomaterials—Techniques and Applications
TL;DR: The immobilization of enzymes, cofactors and whole cells offers the potential of economical exploitation of biomaterial activity and requires the involvement of biochemical, kinetics and reactor design principles.
68
Immobilisierte Biomaterialien — Techniken und Anwendungen
TL;DR: The Immobilisierung von Enzymen, Cofaktoren and ganzen Zellen bietet die Moglichkeit, die Aktivitat of Biomaterialien okonomisch zu nutzen as mentioned in this paper.
32
Reaction engineering parameters for immobilized biocatalysts
Klaus Buchholz
- 01 Jan 1982
TL;DR: The article concentrates on those biochemical engineering parameters of immobilized biocatalysts which are considered important with respect to their application in industrial processes, thus swelling behaviour, mechanical stability, pressure drop and abrasion are stressed.
27
Glucose Isomerase: A Case Study of Enzyme-Catalyzed Process Technology
Bruce K. Hamilton,Clark K. Colton,Charles L. Cooney +2 more
- 01 Jan 1974
TL;DR: The state of the art of glucose isomerase processing as revealed by journal and patent literature is reviewed and assessed in this article, among topics covered are enzyme production, immobilization and stabilization, kinetics, reactor design, and product recovery.
16
References
Effectiveness factors for immobilized-enzyme reactions
M. Moo-Young,Takeshi Kobayashi +1 more
TL;DR: In this article, the effect of intraparticle diffusion in artificial membranes on the kinetic behavior of immobilized enzymes has been considered theoretically in terms of an effectiveness factor, and an approximate equation is proposed for the effectiveness factor when the enzymes obey a Michaelis-Menten relationship.
Über das Zusammenwirken von Strömung, Diffusion und chemischer Reaktion bei der heterogenen Katalyse
TL;DR: In this article, DAMKÖHLER, von E. THIELE, J. B. ZELDOWITSCH et al. present an ansätze von G. DAMKOHLER et al., den E.THIELE sowie J. B.ZELDOWITTSCH zur Berechnung der Konzentrationsunterschiede zwischen dem Inneren von kompaktdispersen Katalysatorkörnern and strömendem Gas werden so umge
Diffusion and Chemical Reaction Velocity as Joint Factors in Determining the Rate of Uptake of Oxygen and Carbon Monoxide by the Red Blood Corpuscle
TL;DR: The most interesting feature of the results was the much slower uptake of O2 by haemoglobin in the intact corpuscle as compared with the of O 2 by ha Hemoglobin in laked solution as previously recorded by Hartridge and Roughton (1925).