Barrel cortex function

TL;DR: This work reveals sparse and spatially intermingled representations of multiple tactile features in mice expressing GCaMP6s and nuclear red fluorescent proteins during performance of a single whisker object localization task and an encoding model related activity to behavioral variables.

TL;DR: Early spontaneous activity patterns control the formation of developing networks in sensory cortices, and disturbances of these activity patterns may lead to long-lasting neuronal deficits.

TL;DR: The potential for the use of known critical and sensitive periods during vertebrate development to investigate and advance the understanding of the neural bases underlying impairments in these developmental disorders of the nervous system is highlighted.

TL;DR: Making whole-cell recordings in primary somatosensory barrel cortex of behaving mice shows that S1 neurons projecting to primary motor cortex and those projecting to secondary somatoensory cortex have distinct intrinsic membrane properties and exhibit markedly different membrane potential dynamics during behavior.

TL;DR: A somatosensory absolute object localization task for head-fixed mice is reported and it is conjecture that this may amplify differences in evoked neural activity between trial types.

TL;DR: The present study bears on afferents that terminate in layer VI of the posteromedial barrel field in the rat, suggesting that the role of corticothalamic pathways should be studied from the viewpoint that sensory perception is an active process which operates under the guidance of motor activities.

TL;DR: Neurons in the supragranular and infragranular layers respond rapidly to changes in sensory experience and may contribute to subsequent modification in layer IV, which supports the hypothesis that the layers of cortex contribute differently to plasticity.

TL;DR: It is demonstrated that distinct intrinsic and corticocortical circuitries arise from barrel and septal columns, indicating that the two subcortical pathways from whiskers to cortex continue as two distinct partially segregated pathways in cortex.