Barrel cortex function

TL;DR: This work reveals sparse and spatially intermingled representations of multiple tactile features in mice expressing GCaMP6s and nuclear red fluorescent proteins during performance of a single whisker object localization task and an encoding model related activity to behavioral variables.

TL;DR: Early spontaneous activity patterns control the formation of developing networks in sensory cortices, and disturbances of these activity patterns may lead to long-lasting neuronal deficits.

TL;DR: The potential for the use of known critical and sensitive periods during vertebrate development to investigate and advance the understanding of the neural bases underlying impairments in these developmental disorders of the nervous system is highlighted.

TL;DR: Making whole-cell recordings in primary somatosensory barrel cortex of behaving mice shows that S1 neurons projecting to primary motor cortex and those projecting to secondary somatoensory cortex have distinct intrinsic membrane properties and exhibit markedly different membrane potential dynamics during behavior.

TL;DR: The anatomy and functional roles of the cerebral cortex are described, but also those of subcortical structures like the striatum, superior colliculus, cerebellum, pontomedullary reticular formation, zona incerta, and anterior pretectal nucleus as well as those of level setting systems like the cholinergic, histaminergic, serotonergic, and noradrenergic pathways.

TL;DR: Two main classes of VPM neurones are document, the most frequently occurring being single‐whisker excitation (SWE) and multi‐ Whisky Excitation (MWE) cells, which exhibited sharper directional tuning than subthreshold EPSPs, which in turn exhibited a sharper directional tuned than IPSPs.

TL;DR: Augmentation and suppression of both spontaneous and evoked activity were found in primary auditory cortex in unanesthetized, paralyzed cats during the performance of a classical conditioning task, having implications for the encoding of acoustic stimuli in terms of the modulation of lemniscal sensory system activity.

TL;DR: The results raise the possibility that, by controlling the activity of intersubnuclear projecting cells, brain regions that project to the spinal trigeminal nuclei may take an active part in selecting the type of vibrissal information that is conveyed through the lemniscal pathway.