Barrel cortex function

TL;DR: This work reveals sparse and spatially intermingled representations of multiple tactile features in mice expressing GCaMP6s and nuclear red fluorescent proteins during performance of a single whisker object localization task and an encoding model related activity to behavioral variables.

TL;DR: Early spontaneous activity patterns control the formation of developing networks in sensory cortices, and disturbances of these activity patterns may lead to long-lasting neuronal deficits.

TL;DR: The potential for the use of known critical and sensitive periods during vertebrate development to investigate and advance the understanding of the neural bases underlying impairments in these developmental disorders of the nervous system is highlighted.

TL;DR: Making whole-cell recordings in primary somatosensory barrel cortex of behaving mice shows that S1 neurons projecting to primary motor cortex and those projecting to secondary somatoensory cortex have distinct intrinsic membrane properties and exhibit markedly different membrane potential dynamics during behavior.

TL;DR: It is found that individual neurons in the cat primary visual cortex can communicate over suprisingly long distances horizontally, in directions parallel to the cortical surface, by combining the techniques of intracellular recording and injection of horseradish peroxidase with three- dimensional computer graphic reconstructions.

TL;DR: This work used two-photon calcium imaging to characterize a functional property—the preferred stimulus orientation—of a group of neurons in the mouse primary visual cortex and large-scale electron microscopy of serial thin sections was used to trace a portion of these neurons’ local network.

TL;DR: This data set provides the first functional description of the excitatory synaptic wiring diagram of a physiologically relevant and anatomically well-defined cortical column at single-cell resolution.

TL;DR: It is shown that the light-gated channel channelrhodopsin-2 (ChR2) is delivered to axons in pyramidal neurons in vivo, and laminar specificity may be identical for local and long-range cortical projections.