Barrel cortex function

TL;DR: This work reveals sparse and spatially intermingled representations of multiple tactile features in mice expressing GCaMP6s and nuclear red fluorescent proteins during performance of a single whisker object localization task and an encoding model related activity to behavioral variables.

TL;DR: Early spontaneous activity patterns control the formation of developing networks in sensory cortices, and disturbances of these activity patterns may lead to long-lasting neuronal deficits.

TL;DR: The potential for the use of known critical and sensitive periods during vertebrate development to investigate and advance the understanding of the neural bases underlying impairments in these developmental disorders of the nervous system is highlighted.

TL;DR: Making whole-cell recordings in primary somatosensory barrel cortex of behaving mice shows that S1 neurons projecting to primary motor cortex and those projecting to secondary somatoensory cortex have distinct intrinsic membrane properties and exhibit markedly different membrane potential dynamics during behavior.

TL;DR: It is suggested that both the strong myelinization and the expanded layer 5 of area AGm may represent cytoarchitectonic specializations related to control of high‐speed whisking behavior.

TL;DR: It is proposed that integration of auditory and somatotopically organized somatosensory modalities reported here may play a role in auditory fear conditioning.

TL;DR: A miniature head-mountable recording device is constructed, with mechanical stabilization achieved by anchoring the recording pipette rigidly in place after the whole-cell configuration is established, which will enable a wide range of new studies involving detailed measurement and manipulation of the physiological properties of identified cells during natural behaviors.

TL;DR: The analysis shows that most cortical APs occur as single APs, although a minor fraction of APs in L2/3 and L5B thick tufted neurons are part of high frequency bursts (15%).