Barrel cortex function

TL;DR: This work reveals sparse and spatially intermingled representations of multiple tactile features in mice expressing GCaMP6s and nuclear red fluorescent proteins during performance of a single whisker object localization task and an encoding model related activity to behavioral variables.

TL;DR: Early spontaneous activity patterns control the formation of developing networks in sensory cortices, and disturbances of these activity patterns may lead to long-lasting neuronal deficits.

TL;DR: The potential for the use of known critical and sensitive periods during vertebrate development to investigate and advance the understanding of the neural bases underlying impairments in these developmental disorders of the nervous system is highlighted.

TL;DR: Making whole-cell recordings in primary somatosensory barrel cortex of behaving mice shows that S1 neurons projecting to primary motor cortex and those projecting to secondary somatoensory cortex have distinct intrinsic membrane properties and exhibit markedly different membrane potential dynamics during behavior.

TL;DR: This review looks at plasticity mechanisms in three periods of life: early post-natal development, adolescence and adulthood, and concludes that horizontal and/or diagonal pathways between barrels are responsible for plasticity expression.

TL;DR: Dazu wurde folgende Aufgabe trainiert: Kleinere Neuronengruppen wurden in vivo mit einer extrazellulären Mikroelektrode gereizt, anderer Tiere wurden nun auf ihre Fähigkeit untersucht, die Aktivität eines einzelnen Neurons wahrzunehmen.

TL;DR: Synaptically coupled layer 2/3 pyramidal neurones located above the same layer 4 barrel (‘barrel‐related’) were investigated using dual whole‐cell voltage recordings in acute slices of rat somatosensory cortex, suggesting that synchronous feed‐forward excitation of L2/3Pyramidal cells arriving from layer 4 could be potentially amplified in layer 1/3 by feedback excitation within a column and then relayed to the neighbouring columns.

TL;DR: The transthalamic corticocortical pathways that can be gated carry information about the cortical processing in one cortical area and also about the motor instructions currently being issued from that area and copied to other cortical areas.