Barrel cortex function

TL;DR: This work reveals sparse and spatially intermingled representations of multiple tactile features in mice expressing GCaMP6s and nuclear red fluorescent proteins during performance of a single whisker object localization task and an encoding model related activity to behavioral variables.

TL;DR: Early spontaneous activity patterns control the formation of developing networks in sensory cortices, and disturbances of these activity patterns may lead to long-lasting neuronal deficits.

TL;DR: The potential for the use of known critical and sensitive periods during vertebrate development to investigate and advance the understanding of the neural bases underlying impairments in these developmental disorders of the nervous system is highlighted.

TL;DR: Making whole-cell recordings in primary somatosensory barrel cortex of behaving mice shows that S1 neurons projecting to primary motor cortex and those projecting to secondary somatoensory cortex have distinct intrinsic membrane properties and exhibit markedly different membrane potential dynamics during behavior.

TL;DR: There is considerable evidence that the basic functional properties of immature cortical networks are conserved through mammalian evolution, making the neonatal rodent an excellent model for studying early cortical activity and associated plasticity during the developmental period corresponding to the human fetal stage.

TL;DR: This paper found that SOM neurons were spontaneously active during periods of quiet wakefulness and hyperpolarized and reduced action potential firing in response to both passive and active whisker sensing, in contrast with all other recorded types of nearby neurons, which were excited by sensory input.

TL;DR: It is found that inhibitory neurons depolarize synchronously with excitatory neurons, but they are much more active with differential contributions of two classes of inhibitory neuron during different brain states.

TL;DR: Two-photon population calcium imaging in awake and subsequently anesthetized rats was used to follow action potential firing in populations of neurons across brain states, and how single neurons contributed to population activity was examined.