Barrel cortex function
Dirk Feldmeyer,Michael Brecht,Fritjof Helmchen,Carl C.H. Petersen,James F.A. Poulet,Jochen F. Staiger,Heiko J. Luhmann,Cornelius Schwarz +7 more
TL;DR: It is argued that in order to understand neocortical function one needs to combine a microscopic view, elucidating the workings of the local columnar microcircuits, with a macroscopic view, which keeps track of the linkage of distant cortical modules in different behavioral contexts.
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About: This article is published in Progress in Neurobiology. The article was published on 01 Apr 2013. and is currently open access. The article focuses on the topics: Barrel cortex & Cortical column.
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Citations
Identification of a developmental switch in information transfer between whisker S1 and S2 cortex in mice
Linbi Cai,Jenq-Wei Yang,Jenq-Wei Yang,Shen-Ju Chou,Chia-Fang Wang,Heiko J. Luhmann,Theofanis Karayannis +6 more
TL;DR: In this article, the authors investigated the developmental engagement of the secondary cortex by sensory stimuli and the emergence of cortico-cortical communication from wS1 to wS2.
Simulation of sensory-evoked signal flow in anatomically realistic models of neural networks
Robert Egger
- 01 Jun 2016
TL;DR: Activation of this model with functional responses measured after whisker touch and simulation of the responses of different neuron types shows that the simulated model responses match experimental measurements, which allowed investigating how robust sensory-evoked responses after different sensory stimuli are formed in different neurons types using computer simulations.
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Thalamocortical Projections Are Significantly Impaired in the R6/2 Mouse Model of Huntington’s Disease
Sandra M. Holley,Katerina D. Oikonomou,Christopher M. Swift,L. Mohan,B. Matthews,Owen M. Vega,G. M. Mkrtchyan,Carlos Cepeda,Michael Levine +8 more
TL;DR: There is a decrease in the transmission of thalamocortical information that is likely because of impaired neurotransmitter release in R6/2 BCTX CPNs, with no genotype-dependent differences in AMPA:NMDA response amplitude ratios.
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The Effects of NMDA Receptor Blockade on Sensory-Evoked Responses in Superficial Layers of the Rat Barrel Cortex
Julia Lebedeva,Andrey Zakharov,Andrey Zakharov,Gulshat Burkhanova,Kseniya Chernova,Roustem Khazipov,Roustem Khazipov +6 more
TL;DR: The results indicate that both non-NMDA and NMDA receptors are involved in sensory signal transmission from L4 to L2/3, and that NMDA-Rs are importantly involved in the generation of the late phase of the sensory-evoked response in supragranular layers.
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