Journal Article10.1016/S0140-6736(03)13693-8
Bacterial meningitis in children
TL;DR: In this paper, a review comprises aspects of the epidemiology, microbiology, pathophysiology, clinical manifestations, diagnosis, management, prognosis, and prevention of bacterial meningitis, with emphasis on the paediatric population.
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About: This article is published in The Lancet. The article was published on 21 Jun 2003. The article focuses on the topics: Meningococcal vaccine & Meningitis.
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Citations
Epidemic meningitis, meningococcaemia, and Neisseria meningitidis.
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Epidemiology, Diagnosis, and Antimicrobial Treatment of Acute Bacterial Meningitis
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References
•Journal Article
Molecular mechanisms of brain damage in bacterial meningitis.
Johann S. Braun,Elaine Tuomanen +1 more
25
Tendencias en la etiología de la meningitis bacteriana aguda en niños chilenos, período 1989-1998.: Impacto de la vacuna anti-H influenzae tipo b (Hib)
José Manuel Díaz P,Lía Catalán N,María Teresa Urrutia L,Valeria Prado J,Walter Ledermann D.,Carmen Mendoza N.,Santiago Topelberg V +6 more
TL;DR: There was a reduction in the incidence of acute bacterial meningitis caused by H influenzae prior to the introduction of the vaccine against H Influenzae type b, and the decrease was more pronounced after the introductionof the vaccine.
20
Prevalence of moderate penicillin resistant invasive Neisseria meningitidis infection in Scotland, 1994-9
TL;DR: The serological characteristics of 774 invasive meningococcal isolates collected through an active laboratory-based surveillance system in Scotland from 1994 to 1999 showed no predominant penicillin resistant serotype/subtype within any serogroup.
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