Journal Article10.1146/ANNUREV.ARPLANT.58.032806.103805
Auxin: The Looping Star in Plant Development
René Benjamins,Ben Scheres +1 more
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TL;DR: This review focuses on the feedback loops that form an integrative part of these regulatory mechanisms in the phytohormone auxin and their role in plant growth and development.
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Abstract: The phytohormone auxin is a key factor in plant growth and development. Forward and reverse genetic strategies have identified important molecular components in auxin perception, signaling, and transport. These advances resulted in the identification of some of the underlying regulatory mechanisms as well as the emergence of functional frameworks for auxin action. This review focuses on the feedback loops that form an integrative part of these regulatory mechanisms.
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Citations
A morphogenetic trigger: is there an emerging concept in plant developmental biology?
Eva Benková,Eva Benková,Maria G. Ivanchenko,Jirÿõ Friml,Jirÿõ Friml,Svetlana Shishkova,Joseph G. Dubrovsky +6 more
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TL;DR: The elp2 mutant affected the expression of key transcription factors and CYCB1 through either acetylation or methylation, and also altered auxin polar transport and reduced auxin content in root.
Mathematical Modelling of the Aux/IAA Negative Feedback Loop
TL;DR: A mathematical model of a single Aux/IAA negative feedback loop in a population of identical cells is developed, which has a single steady-state and identifies the ratio between the Aux/ IAA protein and mRNA turnover rates as a key parameter in the model.
Phylogenomic Analyses of the BARREN STALK1/LAX PANICLE1 (BA1/LAX1) Genes and Evidence for Their Roles During Axillary Meristem Development
TL;DR: Bayesian phylogenetic evidence is presented of a well-supported BA1/LAX1 clade comprised monocots and eudicots, estimating an origin for the lineage at least near the base of flowering plants and lending support to the hypothesis that the same genetic mechanisms regulate the development of different AM types.
Modification of plant hormone levels and signaling as a tool in plant biotechnology.
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References
Local, Efflux-Dependent Auxin Gradients as a Common Module for Plant Organ Formation
Eva Benková,Marta Michniewicz,Michael Sauer,Thomas Teichmann,Daniela Seifertová,Gerd Jürgens,Jiří Friml +6 more
TL;DR: It is shown that organ formation in Arabidopsis involves dynamic gradients of the signaling molecule auxin with maxima at the primordia tips, which suggest that PIN-dependent, local auxin gradients represent a common module for formation of all plant organs, regardless of their mature morphology or developmental origin.
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The F-box protein TIR1 is an auxin receptor
TL;DR: TIR1 is an auxin receptor that mediates Aux/IAA degradation and auxin-regulated transcription and the loss of TIR1 and three related F-box proteins eliminates saturable auxin binding in plant extracts.
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Aux/IAA proteins repress expression of reporter genes containing natural and highly active synthetic auxin response elements.
TL;DR: Cotransfection experiments with natural and synthetic AuxRE reporter genes and effector genes encoding Aux/IAA proteins showed that overexpression of Aux/ IAA proteins in carrot protoplasts resulted in specific repression of TGTCTC Auxre reporter gene expression.
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The PIN auxin efflux facilitator network controls growth and patterning in Arabidopsis roots
Ikram Blilou,Jian Xu,Marjolein Wildwater,Viola Willemsen,Ivan A. Paponov,Jiří Friml,Renze Heidstra,Mitsuhiro Aida,Klaus Palme,Ben Scheres +9 more
TL;DR: This work shows that five PIN genes collectively control auxin distribution to regulate cell division and cell expansion in the primary root and reveals an interaction network of auxin transport facilitators and root fate determinants that control patterning and growth of the root primordium.
Efflux-dependent auxin gradients establish the apical–basal axis of Arabidopsis
Jiří Friml,Anne Vieten,Michael Sauer,Dolf Weijers,Dolf Weijers,Heinz Schwarz,Thorsten Hamann,Thorsten Hamann,Remko Offringa,Gerd Jürgens +9 more
TL;DR: The results indicate how the establishment of cell polarity, polar auxin efflux and local auxin response result in apical–basal axis formation of the embryo, and thus determine the axiality of the adult plant.
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