Journal Article10.1146/ANNUREV.ARPLANT.58.032806.103805
Auxin: The Looping Star in Plant Development
René Benjamins,Ben Scheres +1 more
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TL;DR: This review focuses on the feedback loops that form an integrative part of these regulatory mechanisms in the phytohormone auxin and their role in plant growth and development.
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Abstract: The phytohormone auxin is a key factor in plant growth and development. Forward and reverse genetic strategies have identified important molecular components in auxin perception, signaling, and transport. These advances resulted in the identification of some of the underlying regulatory mechanisms as well as the emergence of functional frameworks for auxin action. This review focuses on the feedback loops that form an integrative part of these regulatory mechanisms.
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Citations
Gibberellin Regulates PIN-FORMED Abundance and Is Required for Auxin Transport–Dependent Growth and Development in Arabidopsis thaliana
TL;DR: It is shown that auxin transport is reduced in the inflorescences of Arabidopsis thaliana mutants deficient in GA biosynthesis and signaling, and that PIN protein levels recover to wild-type levels following GA treatment.
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Systems Analysis of Auxin Transport in the Arabidopsis Root Apex
Leah R. Band,Darren M. Wells,John A. Fozard,Teodor Ghetiu,Andrew P. French,Michael P. Pound,Michael Wilson,Lei Yu,Wenda Li,Hussein I. Hijazi,Jaesung Oh,Simon P. Pearce,Miguel A. Perez-Amador,Jeonga Yun,Eric M. Kramer,Jose M. Alonso,Christophe Godin,Teva Vernoux,T. Charlie Hodgman,Tony P. Pridmore,Ranjan Swarup,John R. King,Malcolm J. Bennett +22 more
TL;DR: An auxin transport model based on actual root cell geometries and carrier subcellular localizations is developed and tested using the DII-VENUS auxin sensor and concludes that the nonpolar AUX1/LAX influx carriers control which tissues have high auxin levels, whereas the polar PIN carriers control the direction of Auxin transport within these tissues.
Protein-protein interaction and gene co-expression maps of ARFs and Aux/IAAs in Arabidopsis.
TL;DR: The objective of this study was to generate the Aux/IAA-ARF protein-protein interaction map using full length sequences and locate the interacting protein pairs to specific gene co-expression networks in order to define tissue-specific responses of the auxin-inducible genes of the Aux-Aux/ARF interactome.
Walls are thin 1 (WAT1), an Arabidopsis homolog of Medicago truncatula NODULIN21, is a tonoplast-localized protein required for secondary wall formation in fibers.
Philippe Ranocha,Nicolas Denancé,Ruben Vanholme,Amandine Freydier,Yves Martinez,Laurent Hoffmann,Lothar Köhler,Cécile Pouzet,Jean-Pierre Renou,Björn Sundberg,Wout Boerjan,Deborah Goffner +11 more
TL;DR: In this paper, a new upstream component of secondary wall formation in xylary and interfascicular fibers was identified by combining Zinnia elegans in vitro tracheary element genomics with reverse genetics in Arabidopsis, and the secondary wall phenotype was supported by comparative transcriptomic and metabolomic analyses of wat1 and wild-type stems.
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Arabidopsis Tyrosylprotein Sulfotransferase Acts in the Auxin/PLETHORA Pathway in Regulating Postembryonic Maintenance of the Root Stem Cell Niche
Wenkun Zhou,Lirong Wei,Jian Xu,Jian Xu,Qingzhe Zhai,Hongling Jiang,Rong Chen,Qian Chen,Jiaqiang Sun,Jinfang Chu,Lihuang Zhu,Chun-Ming Liu,Chuanyou Li +12 more
TL;DR: It is shown that TPST expression is positively regulated by auxin and that mutation of this gene affects auxin distribution by reducing local expression levels of several PIN genes and auxin biosynthetic genes in the stem cell niche region, and that overexpression of PLT2 rescues the root meristem defects of the loss-of-function mutant of TPST.
References
Local, Efflux-Dependent Auxin Gradients as a Common Module for Plant Organ Formation
Eva Benková,Marta Michniewicz,Michael Sauer,Thomas Teichmann,Daniela Seifertová,Gerd Jürgens,Jiří Friml +6 more
TL;DR: It is shown that organ formation in Arabidopsis involves dynamic gradients of the signaling molecule auxin with maxima at the primordia tips, which suggest that PIN-dependent, local auxin gradients represent a common module for formation of all plant organs, regardless of their mature morphology or developmental origin.
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The F-box protein TIR1 is an auxin receptor
TL;DR: TIR1 is an auxin receptor that mediates Aux/IAA degradation and auxin-regulated transcription and the loss of TIR1 and three related F-box proteins eliminates saturable auxin binding in plant extracts.
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Aux/IAA proteins repress expression of reporter genes containing natural and highly active synthetic auxin response elements.
TL;DR: Cotransfection experiments with natural and synthetic AuxRE reporter genes and effector genes encoding Aux/IAA proteins showed that overexpression of Aux/ IAA proteins in carrot protoplasts resulted in specific repression of TGTCTC Auxre reporter gene expression.
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The PIN auxin efflux facilitator network controls growth and patterning in Arabidopsis roots
Ikram Blilou,Jian Xu,Marjolein Wildwater,Viola Willemsen,Ivan A. Paponov,Jiří Friml,Renze Heidstra,Mitsuhiro Aida,Klaus Palme,Ben Scheres +9 more
TL;DR: This work shows that five PIN genes collectively control auxin distribution to regulate cell division and cell expansion in the primary root and reveals an interaction network of auxin transport facilitators and root fate determinants that control patterning and growth of the root primordium.
Efflux-dependent auxin gradients establish the apical–basal axis of Arabidopsis
Jiří Friml,Anne Vieten,Michael Sauer,Dolf Weijers,Dolf Weijers,Heinz Schwarz,Thorsten Hamann,Thorsten Hamann,Remko Offringa,Gerd Jürgens +9 more
TL;DR: The results indicate how the establishment of cell polarity, polar auxin efflux and local auxin response result in apical–basal axis formation of the embryo, and thus determine the axiality of the adult plant.
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