Book Chapter10.1385/1-59259-809-9:353
Automated NMR structure calculation with CYANA.
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TL;DR: This chapter gives an introduction to automated nuclear magnetic resonance (NMR) structure calculation with the program CYANA.
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Abstract: This chapter gives an introduction to automated nuclear magnetic resonance (NMR) structure calculation with the program CYANA. Given a sufficiently complete list of assigned chemical shifts and one or several lists of cross-peak positions and columns from two-, three-, or four-dimensional nuclear Overhauser effect spectroscopy (NOESY) spectra, the assignment of the NOESY cross-peaks and the three-dimensional structure of the protein in solution can be calculated automatically with CYANA.
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Citations
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The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor.
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A Sterile α-Motif Domain in NafY Targets Apo-NifDK for Iron-Molybdenum Cofactor Delivery via a Tethered Domain
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TL;DR: In silico studies indicated that the introduction of a hydrocarbon staple vs. a lactam bridge likely perturbs critical interactions required for proper binding of the peptide to the Li-TryR monomer.
A novel approach for protein structure prediction based on an estimation of distribution algorithm
Amir Morshedian,Jafar Razmara,Shahriar Lotfi +2 more
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TL;DR: AHEDA uses the hydrophobic-polar model to develop a robust and efficient evolutionary-based algorithm for protein structure prediction that combines an integrated estimation of distribution algorithm and a stochastic local search to improve its accuracy.
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