Association between fecal microbiota and generalized anxiety disorder: Severity and early treatment response.

TL;DR: In this article, the authors summarize the mechanisms whereby the gut microbiota regulate the production, transportation, and functioning of neurotransmitters, and discuss how microbiome dysbiosis affects cognitive function, especially in neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

TL;DR: In this paper, the authors conducted an umbrella and updated meta-analysis of gut microbiota alterations in general adult psychiatric populations and performed a within-and between-diagnostic comparison, concluding that gut microbiota perturbations were associated with a transdiagnostic pattern with a depletion of certain anti-inflammatory butyrate-producing bacteria and an enrichment of pro-inflammatory bacteria in patients with depression, bipolar disorder, schizophrenia, and anxiety.

TL;DR: The results support a link between MDD and lower levels of anti-inflammatory, butyrate-producing bacteria, and may support a connection between the gut microbiota and the chronic, low-grade inflammation often observed in MDD patients.

TL;DR: The evolutionary relationships between Shigella spp.

TL;DR: This review focuses on age-related changes in GI physiology and function, changes of the intestinal microbiota with ageing and frailty, how these are associated and how intestinal microbiota-targeted interventions may counteract these changes.

TL;DR: This review serves as a systematic guide to the genetics of generalized anxiety disorder (GAD) and further focuses on anxiety-relevant endophenotypes, such as pathological worry fear of uncertainty, and neuroticism.

TL;DR: It is suggested that kaempferol might be a promising neuroprotective agent for alleviating inflammatory responses and BBB dysfunction by inhibiting HMGB1 release and down‐regulating TLR4/MyD88 inflammatory pathway.