Journal Article10.1056/NEJM200103153441104
Appendectomy and protection against ulcerative colitis.
444
TL;DR: Appendectomy for an inflammatory condition ( appendicitis or lymphadenitis) but not for nonspecific abdominal pain is associated with a low risk of subsequent ulcerative colitis, and this inverse relation is limited to patients who undergo surgery before the age of 20 years.
read more
Abstract: Background: A history of appendectomy is rare in patients with ulcerative colitis. This suggests a protective effect of appendectomy or that appendicitis and ulcerative colitis are alternative infl ...
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Appendicitis (General Pediatric Surgery of Abdomen)
Alan E. Mortell,David Coyle +1 more
- 01 Jan 2020
TL;DR: Laroscopic appendectomy has several advantages over open appendectomy regarding postoperative pain control, ileus, return to diet, and duration of hospital stay, and is thus becoming a more frequently used operative modality for appendicitis.
2
Immunological changes at rectal mucosa in appendectomised subjects and inhabitants of developing countries.
TL;DR: The CD8+ increase is the only common significant alteration in the mucosa of both groups protected against the development of ulcerative colitis, suggesting that the factors causing changes in lamina propria lymphocytes of both group are different.
2
•Dissertation
Immunological mechanisms underlying inflammatory bowel disease
Ludvig Linton
- 29 Apr 2015
TL;DR: It is shown that chemokine receptor interactions are important for colonic immune responses during IBD, and CD4 + T helper cells infiltrating the colonic mucosa during inflammation, and CCR9 is widely expressed on these cells, indicating importance role during human colitis.
Représentations des médicaments et des médecines complémentaires et alternatives chez les patients MICI
Kévin Girard
- 27 Oct 2014
TL;DR: The authors found that patients expriment une perte de confiance and un sentiment de mefiance envers le medicament, en lien avec une discordance entre les effets attendus du medicament (guerison, rapidite d'action, efficacite) and les effet percus (effets indesirables a court and long terme, manque d'efficacite).
2
References
The epidemiology of appendicitis and appendectomy in the united states
TL;DR: The authors analyzed National Hospital Discharge Survey data for the years 1979-1984 to describe the epidemiology of appendicitis and appendectomy in the United States and found that for the elderly, the preventive value of an incidental procedure is considerably lower.
A meta-analysis of the role of smoking in inflammatory bowel disease.
TL;DR: There is no justification for health care providers to change the Surgeon General's recommendations on smoking or tobacco use for ulcerative colitis patients specifically and a review of the literature, meta-analysis of selected studies, and assessment of causality criterion suggest that not smoking and ulceratives colitis and smoking and Crohn's disease are consistent with a causal relationship.
685
Role of appendix in the development of inflammatory bowel disease in TCR-alpha mutant mice.
TL;DR: It is suggested that ALF, rather than PP, is the priming site of cells involved in the disease process and plays an important role in the development of IBD in TCR-alpha-/- mice.
269
Appendectomy protects against ulcerative colitis.
Laura E. Derby,Hershel Jick +1 more
TL;DR: Appendectomy appears to protect against ulcerative colitis, and a random sample of 100 cases and 100 controls to validate the subject's history of appendectomy confirmed this.
130
Appendiceal orifice inflammation as a skip lesion in ulcerative colitis: an analysis in relation to medical therapy and disease extent
Suk-Kyun Yang,Hwoon-Yong Jung,Gyeong Hoon Kang,Young Min Kim,Seung-Jae Myung,Ki Nam Shim,Weon-Seon Hong,Young Il Min +7 more
TL;DR: Appendiceal orifice inflammation as a skip lesion of ulcerative colitis is not rare, is more frequently observed in patients with less extensive disease, and is not the result of patchy improvement due to medical therapy.
109