Journal Article10.1056/NEJM200103153441104
Appendectomy and protection against ulcerative colitis.
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TL;DR: Appendectomy for an inflammatory condition ( appendicitis or lymphadenitis) but not for nonspecific abdominal pain is associated with a low risk of subsequent ulcerative colitis, and this inverse relation is limited to patients who undergo surgery before the age of 20 years.
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Abstract: Background: A history of appendectomy is rare in patients with ulcerative colitis. This suggests a protective effect of appendectomy or that appendicitis and ulcerative colitis are alternative infl ...
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Use of Corticosteroids, Other Immunosuppressive Therapies, and Tonsillectomy in the Treatment of IgA Nephropathy
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Histological and immunological features of appendix in patients with ulcerative colitis.
Yukihiko Jo,Takayuki Matsumoto,Shinichiro Yada,Shotaro Nakamura,Takashi Yao,Masayuki Hotokezaka,Ryuichi Mibu,Mitsuo Iida +7 more
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45
References
The epidemiology of appendicitis and appendectomy in the united states
TL;DR: The authors analyzed National Hospital Discharge Survey data for the years 1979-1984 to describe the epidemiology of appendicitis and appendectomy in the United States and found that for the elderly, the preventive value of an incidental procedure is considerably lower.
A meta-analysis of the role of smoking in inflammatory bowel disease.
TL;DR: There is no justification for health care providers to change the Surgeon General's recommendations on smoking or tobacco use for ulcerative colitis patients specifically and a review of the literature, meta-analysis of selected studies, and assessment of causality criterion suggest that not smoking and ulceratives colitis and smoking and Crohn's disease are consistent with a causal relationship.
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Role of appendix in the development of inflammatory bowel disease in TCR-alpha mutant mice.
TL;DR: It is suggested that ALF, rather than PP, is the priming site of cells involved in the disease process and plays an important role in the development of IBD in TCR-alpha-/- mice.
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Appendectomy protects against ulcerative colitis.
Laura E. Derby,Hershel Jick +1 more
TL;DR: Appendectomy appears to protect against ulcerative colitis, and a random sample of 100 cases and 100 controls to validate the subject's history of appendectomy confirmed this.
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Appendiceal orifice inflammation as a skip lesion in ulcerative colitis: an analysis in relation to medical therapy and disease extent
Suk-Kyun Yang,Hwoon-Yong Jung,Gyeong Hoon Kang,Young Min Kim,Seung-Jae Myung,Ki Nam Shim,Weon-Seon Hong,Young Il Min +7 more
TL;DR: Appendiceal orifice inflammation as a skip lesion of ulcerative colitis is not rare, is more frequently observed in patients with less extensive disease, and is not the result of patchy improvement due to medical therapy.
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