Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases

TL;DR: This poster aims to demonstrate the efforts towards in-situ applicability of EMMARM, which aims to provide real-time information about the physical and cognitive properties of Alzheimer's disease and other dementias.

TL;DR: There is a need for accurate determination of individual's oxidative stress levels before prescribing the supplement antioxidants, as both extremes, oxidative and antioxidative stress, are damaging.

TL;DR: Findings indicate that alcohol impacts many disease outcomes causally, both chronic and acute, and injuries, and a pattern of heavy episodic drinking increases risk for some disease and all injury outcomes.

TL;DR: The caveats of the traditional mitochondrial free radical theory of aging are discussed and other possible mechanisms, including insulin/IGF-1 signaling and the target of rapamycin pathways, that underlie the central role of mitochondria in the aging process are highlighted.

TL;DR: The QUOROM Statement (QUality Of Reporting Of Meta-analyses) as mentioned in this paper was developed to address the suboptimal reporting of systematic reviews and meta-analysis of randomized controlled trials.

TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.

TL;DR: This paper examines eight published reviews each reporting results from several related trials in order to evaluate the efficacy of a certain treatment for a specified medical condition and suggests a simple noniterative procedure for characterizing the distribution of treatment effects in a series of studies.

TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.