Antibacterial effect of some wild medicinal plants in Palestine against multidrug resistant Escherichia coli clinical isolate
Lubna Abdallah,Ghadeer Omar +1 more
TL;DR: The efficacy of using some plant extracts as natural antibacterial alternatives against multidrug resistant clinical isolate of Escherichia coli is confirmed and the possibility of using them as drugs for the treatment of other multidrog resistant bacterial isolates is suggested.
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Abstract: \n Due to the emergence of antibiotic resistant pathogens, plants are being an excellent alternate to fight the further spread of multidrug resistant microorganisms. In this study, six plant species grown wildly in Palestine were used to determine their efficacy against multidrug resistant clinical isolate of Escherichia coli. The dried areal parts of Calamintha incana, Lupins pilosus, Parietaria judica, Satureja thymbra, Thymbra spicata and Verbascum fruticulosum were extracted with water, ethanol and methanol solvents. All extracts were screened for their antibacterial activity using micro-dilution method. Plant extraction with alcohol solvents provided stronger antibacterial effect compared to the aqueous ones. All alcoholic extracts have an inhibitory effect against E. coli except the ethanol extract of L. pilosus and the methanol extracts of V. fruticulosum and C. incana. Moreover, C. incana aqueous extract was the only aqueous extract with bacteriostatic activity. Among the studied plant species, ethanol extract of T. spicata was the most potent one with MBC value 12.5 mg/mL. However, P. judica ethanol extract which exhibited the best MIC effect (6.25 mg/mL) killed E. coli isolate at a 25 mg/mL. In conclusion, obtained results confirmed the efficacy of using some plant extracts as natural antibacterial alternatives. Therefore, it suggests the possibility of using them as drugs for the treatment of other multidrug resistant bacterial isolates.\n
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Review on the Antibacterial Mechanism of Plant-Derived Compounds against Multidrug-Resistant Bacteria (MDR).
TL;DR: In this article, a review of antibiotic resistance strategies produced by multidrug-resistant bacteria and phytochemicals from different classes with documented antimicrobial action against resistant bacteria, either alone or in combination with traditional antibiotics is presented.
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Masita Arip,Malarvili Selvaraja,M. R,Lee Fang Tan,Mun Yee Leong,Puay Luan Tan,Vicencio Yap,S Chinnapan,Ng Chin Tat,Maha Abdullah,Dharmendra K,Najwan K. Jubair +11 more
TL;DR: The importance of plant and secondary metabolites as a possible solution for AMR together with their mechanisms of action is discussed, as well as to identify currently available pharmacological therapies against microbes and AMR.
Escherichia coli as a pathogen in dogs and cats [Escherichia coli infections, diarrhoea, extra-intestinal diseases, virulence factors]
L. Beutin
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TL;DR: The role of dogs and cats as transmission vectors of pathogenic E. coli strains to other animals and humans was investigated in this paper. But the authors did not find any evidence of transmission between dogs and humans.
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Antibacterial, Anticandidal, Phytochemical, and Biological Evaluations of Pellitory Plant
Mohammad Qadi,Nidal Jaradat,Saad Al-Lahham,Iyad Ali,Murad Abualhasan,Naser Shraim,Fatima Hussein,Linda Issa,Ahmed Mousa,Abdalraziq Zarour,Amani Badrasawi,Aseel M Baarah,Reem Al-Omari +12 more
TL;DR: Assessment of the phytoconstituents, antilipase, antiamylase, antimicrobial, and cytotoxic characters of the Pellitory plant showed that the methanol fraction has strong α-amylase and lipase inhibitory characters, and can serve as an effective source of natural products to develop new antiobesity, antidiabetic, antimacterial, and anticancer agents.
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