Patent
Anti-inflammatory compounds
Yousef Al-Abed,Kevin J. Tracey +1 more
- 07 Oct 2004
11
TL;DR: In this article, a method of treating a subject with an inflammatory cytokine-mediated disorder comprising administering to the subject a compound of Formulae (Ia) or (VIIa) was described.
read more
Abstract: Compounds of Formula (I), pharmaceutical compositions comprising compounds of Formulae (Ia) or (VII) and a method of treating a subject with an inflammatory cytokine-mediated disorder comprising administering to the subject a compound of Formulae (Ia) or (VIIa). The variables of Formulae (I), (Ia), (VII) and (VIIa) are described herein.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Patent
Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
Wilfried Lubisch,Wilfried Hornberger,Thorsten Oost,Daryl R. Sauer,Liliane Unger,Wolfgang Wernet,Hervé Geneste +6 more
- 30 Sep 2004
TL;DR: In this article, the 1,3-dihydroindol-2-one (oxindole) derivatives of the formula (I) in which A, R 3, R 4, R 5 R 6 and R 7 are defined according to claim 1, and to medicaments containing them for the treatment of diseases.
52
Patent
Pharmaceutical compositions and their methods of use
Murali Gopalakrishnan,Marie P. Honore,Chih-Hung Lee,John Malysz,Jianguo Ji,Tao Li,Michael R. Schrimpf,Kevin B. Sippy,David J. Anderson +8 more
- 12 Dec 2007
TL;DR: In this article, a composition comprising a neuronal nicotinic receptor ligand and an α4β2 positive allosteric modulator, a method of using the same, and a related article of manufacture was described.
32
Patent
Novel 1,2,4 oxadiazole compounds and methods of use thereof
Jianguo Ji,Chih-Hung Lee,Kevin B. Sippy,Tao Li,Murali Gopalakrishnan +4 more
- 06 Jun 2008
TL;DR: In this paper, the authors describe 1 2,4 oxadiazole compounds and analogs thereof, represented by formula (II) and compositions and methods of use thereof, as well as their use.
26
Patent
Detection of lysophosphatidylcholine for prognosis or diagnosis of a systemic inflammatory condition
Song Q. Shi,Thomas Matthew Gentle,Richard L. Moore +2 more
- 27 Sep 2006
TL;DR: In this paper, the authors present methods and compositions useful for the diagnosis or prognosis of a systemic inflammatory condition such as sepsis, such as systemic inflammatory conditions such as Crohn's disease.
23
Patent
Substituted oxindole derivatives and their use as vasopressin receptor ligands
Astrid Netz,Thorsten Oost,Hervé Geneste,Wilfried Braje,Wolfgang Wernet,Liliane Unger,Wilfried Hornberger,Wilfried Lubisch +7 more
- 28 Dec 2007
TL;DR: In this article, a novel oxindole derivatives of the general formula (I) to medicaments comprising them and their use for the prophylaxis and/or treatment of diseases vasopressin dependent.
19
References
Patent
3, 5-disubstituted and 3, 4, 5-trisubstituted 2-isoxazolines and isoxazoles, process for their preparation and their use as pharmaceuticals
Wilfried Schwab,Anagnostopulos Hiristo,Bartlett Robert R,Rudolf Schleyerbach,Klaus Ulrich Dr Weithmann +4 more
- 03 Mar 1995
TL;DR: A compound having the formula (I), a physiologically tolerable salt of the compound (I) and/or a steroisomeric form (I, R1 or R2) in which one residue residue stands for the formula(II), are suitable for preparing medicaments for the therapy of inflammations, asthma, rheumatoid diseases and auto-immune diseases as discussed by the authors.
16