Journal Article10.1016/0002-8703(75)90082-4
Angiotensin- and norepinephrine-induced myocardial lesions: experimental and clinical studies in rabbits and man.
H. Gavras,D. Kremer,J. J. Brown,Brenda Gray,A. F. Lever,R. F. Macadam,A. Medina,J. J. Morton,J. I. S. Robertson +8 more
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TL;DR: The ability of large doses of exogenous angiotensin II to cause widespread multifocal microscopic myocardial necrosis in the rabbit has been confirmed and cardiac attacks in these five patients all occurred during or shortly after procedures, such as sodium-depleting dialysis, renal artery surgery, or diazoxide administration, known to cause increase in plasma concentrations of renin and angiotensor II.
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About: This article is published in American Heart Journal. The article was published on 01 Mar 1975. The article focuses on the topics: Angiotensin II & Renal artery.
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Citations
Norepinephrine spillover to plasma in patients with congestive heart failure: evidence of increased overall and cardiorenal sympathetic nervous activity.
TL;DR: There is marked regional variation, inapparent from measurements of plasma norepinephrine concentration, in sympathetic nerve activity in patients with congestive heart failure.
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Medical Therapy Can Improve the Biological Properties of the Chronically Failing Heart A New Era in the Treatment of Heart Failure
TL;DR: In subjects with idiopathic dilated or ischemic cardiomyopathy, antiadrenergic therapy with beta-blocking agents appears to be able to partially reverse systolic dysfunction and ventricular remodeling, and the precise mechanisms underlying this latter effect have not yet been elucidated.
498
Cardiac myocyte necrosis induced by angiotensin II.
TL;DR: The role of Angiotensin II (Ang II) in the pathogenesis and progression of the failing heart is uncertain, and previous reports have suggested that myocyte injury may be a component in this process.
432
Peripartum myocarditis and cardiomyopathy.
TL;DR: In patients with peripartum cardiomyopathy, the etiology remains unclear although myocarditis was present in 78% of those with this condition, and resolution of mycarditis is associated with significant improvement in left ventricular function.
254
Neuroendocrine activation after acute myocardial infarction.
TL;DR: Heart failure, ventricular tachycardia, and deaths were associated with extensive myocardial infarction, low left ventricular ejection fraction, and persistently high concentrations of catecholamines, renin, and angiotensin II up to 10 days after admission, whereas in uncomplicated cases concentrations had already returned to normal.
218
References
A New Electrocardiographic Pattern Observed in Cerebrovascular Accidents
TL;DR: An electrocardiographic pattern was encountered in patients with cerebrovascular accidents which consisted of T waves of large amplitude and duration and the prolonged Q-T interval associated with the pattern was most probably a Q-U interval.
406
The action of peptides on the adrenal medulla. release of adrenaline by bradykinin and angiotensin.
W. Feldberg,G. P. Lewis +1 more
TL;DR: The present experiments show that bradykinin and angiotensin are potent releasers of the medullary hormones, probably mainly adrenaline, from the suprarenal glands, and ang Elliotensin is more potent in this respect than any other known substance.
355
Estimation of Angiotensin II Concentration in Human Plasma by Radioimmunoassay. Some Applications to Physiological and Clinical States
G. Düsterdieck,G. McElwee +1 more
TL;DR: A radioimmunoassay method for the measurement of angiotensin II in human plasma is described and the hormone is extracted quickly by Dowex (H+) particles.
281
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