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Analyzing Microarray Gene Expression Data
Geoffrey J. McLachlan,Kim Anh Do,Christophe Ambroise +2 more
- 04 Aug 2004
875
TL;DR: In this article, the authors proposed a supervised classification of Tissue Samples and linked the supervised classification with survival analysis, and showed that the classification of tissue samples is more accurate than that of microarray data.
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Abstract: Preface. 1. Microarrays in Gene Expression Studies. 2. Cleaning and Normalization. 3. Some Cluster Analysis Methods. 4. Clustering of Tissue Samples. 5. Screening and Clustering of Genes. 6. Discriminant Analysis. 7. Supervised Classification of Tissue Samples. 8. Linking Microarray Data with Survival Analysis. References. Author Index. Subject Index.
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Citations
A Machine Learning System for Understanding Appraisal in Design Documents
Jianxiong Wang,Jenny Turner,Geoff McLachlan +2 more
- 01 Jan 2009
TL;DR: This thesis describes a machine learning system for understanding appraisal in design documents that expresses the positive or negative stance of the author to the semantic meaning of the document.
4
Identifying subset of genes that have influential impacts on cancer progression: a new approach to analyze cancer microarray data
Mingyu Shi,Shuangge Ma +1 more
TL;DR: Analysis of two lymphoma studies shows that the proposed approach – which is composed of the hybrid gene clustering, linear regression model for survival, and clustering regularized estimation with CTGDR – can effectively identify gene clusters and genes within selected clusters that have satisfactory predictive power for censored cancer survival outcomes.
4
Fast Transient Classification With a ParallelizedTemperature Modulated E-Nose
Hernandez Bennetts,Victor Manuel +1 more
- 01 Jan 2010
TL;DR: A novel operating principle for a temperature modulatedelectronic nose is introduced and the main goal is to perform gas discrimination with metal oxide gas sensors withTemperature modulated electronic nose.
In silico construction of a protein interaction landscape for nucleotide excision repair
Nancy Tran,Pingping Qu,Dennis A. Simpson,Laura A. Lindsey-Boltz,Xiaojun Guan,Charles Schmitt,Joseph G. Ibrahim,William K. Kaufmann +7 more
TL;DR: A systems-level perspective on the topological and functional relationships among proteins contributing to nucleotide excision repair in Saccharomyces cerevisiae is obtained and a computational framework that can be applied to construct landscapes for other biological processes is offered.