An immunochemical marker of low density lipoprotein oxidation.
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TL;DR: It appears that the enhancement of immunoreactivity of the C-terminus of apoB is a general phenomenon associated with various kinds of oxidative modifications of LDL.
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About: This article is published in Journal of Lipid Research. The article was published on 01 Jun 1989. and is currently open access. The article focuses on the topics: Apolipoprotein B & Low-density lipoprotein.
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Citations
The role of lipid peroxidation and antioxidants in oxidative modification of LDL.
TL;DR: A comprehensive survey on the compositional properties of LDL relevant for its susceptibility to oxidation, on the mechanism and kinetics of LDL oxidation, and on the chemical and physico-chemical properties of HDL oxidized by exposure to copper ions is provided.
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Oxidized low density lipoproteins: a role in the pathogenesis of atherosclerosis in diabetes?
TL;DR: ’ One hypothesis is that increased post-synthetic, chemical, modification of LDL, by oxidation, glycosylation, or both, may induce endothelial injury and/or accelerate foam cell formation by rnonocyte-macrophages in the arterial intima.
276
Glycation and oxidation: a role in the pathogenesis of atherosclerosis
TL;DR: Together glycation and oxidation, "glycoxidation," occurs when oxidative reactions affect the initial products of glycation, and results in irreversible structural alterations of proteins, of greatest significance in long-lived proteins such as collagen.
250
Scavenger receptor-independent stimulation of cholesterol esterification in macrophages by low density lipoprotein extracted from human aortic intima.
TL;DR: Results indicate that the accelerated uptake by macrophages of LDL isolated from the arterial intima can largely be attributed to phagocytosis of LDL-containing aggregates.
158
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