An efficient Jacobian reduction method for diffuse optical image reconstruction.
TL;DR: By removing regions within the inverse model whose contribution to the measured data is less than 1%, it has no significant effect upon the estimated inverse problem, but does provide up to a 14 fold improvement in computational time.
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Abstract: Model based image reconstruction in Diffuse Optical Tomography relies on both the numerical accuracy of the forward model as well as the computational speed and efficiency of the inverse model Most model based image reconstruction algorithms rely on Newton type inversion methods, whereby the inverse of a large Jacobian is approximated In this work we present an efficient Jacobian reduction method which takes into account the total sensitivity of the imaging domain to the measured boundary data It is shown using numerical and phantom data that by removing regions within the inverse model whose contribution to the measured data is less than 1%, it has no significant effect upon the estimated inverse problem, but does provide up to a 14 fold improvement in computational time
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Fast segmentation and high-quality three-dimensional volume mesh creation from medical images for diffuse optical tomography.
Michael Jermyn,Hamid R. Ghadyani,Michael A. Mastanduno,Wesley David Turner,Scott C. Davis,Hamid Dehghani,Hamid Dehghani,Brian W. Pogue +7 more
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References
Optical tomography in medical imaging
TL;DR: A review of methods for the forward and inverse problems in optical tomography can be found in this paper, where the authors focus on the highly scattering case found in applications in medical imaging, and to the problem of absorption and scattering reconstruction.
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Recent advances in diffuse optical imaging.
TL;DR: The current state-of-the-art of diffuse optical imaging is reviewed, which is an emerging technique for functional imaging of biological tissue and recent work on in vivo applications including imaging the breast and brain is reviewed.
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Retinotopic mapping of adult human visual cortex with high-density diffuse optical tomography
TL;DR: A high-performance, high-density diffuse optical tomography (DOT) system that overcomes previous limitations and enables superior image quality and the utility of the DOT system is shown by presenting functional hemodynamic maps of the adult human visual cortex.
Diffuse optical tomography of breast cancer during neoadjuvant chemotherapy: a case study with comparison to MRI.
Regine Choe,Alper Corlu,Kijoon Lee,Turgut Durduran,Soren D. Konecky,Monika Grosicka-Koptyra,Simon R. Arridge,Brian J. Czerniecki,Douglas L. Fraker,Angela DeMichele,Britton Chance,Mark A. Rosen,Arjun G. Yodh +12 more
TL;DR: Measurements reveal tumor shrinkage during the course of chemotherapy, in reasonable agreement with magnetic resonance images of the same subject, and demonstrate the potential of DOT for measuring physiological parameters of breast lesions during chemotherapy.
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