An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest.

TL;DR: The main finding in this study is that age-related decline in cortical thickness is widespread, but shows an anterior-posterior gradient with frontal and parietal regions, in general, exhibiting greater rates of decline than temporal and occipital regions.

TL;DR: This is the first report to use DTI to show the structural connectomic alterations present in MDD, and highlights that altered structural connectivity between nodes of the default mode network and the frontal-thalamo-caudate regions are core neurobiological features associated with MDD.

TL;DR: It is shown that in general Ward’s clustering performs better than alternative methods with regard to reproducibility and accuracy and that the two criteria diverge regarding the preferred models (reproducibility leading to more conservative solutions), thus deferring the practical decision to a higher level alternative, namely the choice of a trade-off between accuracy and stability.

TL;DR: Whether clinically normal older individuals with Aβ deposition revealed by positron emission tomography imaging using Pittsburgh Compound B also have evidence of both cortical thickness and hippocampal volume reductions in a pattern similar to that seen in AD is investigated.

TL;DR: An anatomical parcellation of the spatially normalized single-subject high-resolution T1 volume provided by the Montreal Neurological Institute was performed and it is believed that this tool is an improvement for the macroscopical labeling of activated area compared to labeling assessed using the Talairach atlas brain.

TL;DR: A set of automated procedures for obtaining accurate reconstructions of the cortical surface are described, which have been applied to data from more than 100 subjects, requiring little or no manual intervention.

TL;DR: In this article, the authors propose three basic concepts: devising the items, selecting the items and selecting the responses, from items to scales, reliability and validity of the responses.