Journal Article10.1016/J.ACA.2011.06.017
Ambient ionization mass spectrometry: a tutorial.
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TL;DR: This tutorial paper provides a review of the publications related to ambient ionization techniques and describes the underlying principles of operation, ionization processes, detecting mass ranges, sensitivity, and representative applications of these techniques.
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About: This article is published in Analytica Chimica Acta. The article was published on 19 Sep 2011. The article focuses on the topics: Ambient ionization & Desorption electrospray ionization.
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References
Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization
TL;DR: The DESI phenomenon was observed both in the case of conductive and insulator surfaces and for compounds ranging from nonpolar small molecules such as lycopene, the alkaloid coniceine, and small drugs, through polar compounds such as peptides and proteins.
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Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions
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Ambient Mass Spectrometry
TL;DR: In DESI as discussed by the authors, electrically charged droplets are directed at the ambient object of interest; they release ions from the surface, which are then vacuumed through the air into a conventional mass spectrometer.
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Fast atom bombardment of solids (F.A.B.): a new ion source for mass spectrometry
TL;DR: A method for obtaining high-quality mass spectra of molecules which previously were difficult or impossible to study by ionisation methods is described in this paper, where a new method is proposed to obtain high quality mass spectras of molecules.
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Electrospray ionization mass spectrometry : fundamentals, instrumentation, and applications
Richard B. Cole
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TL;DR: In this article, Kebarle et al. discuss the mechanism of electrospray mass spectrometers and discuss the application of electrosphere ionization in PEptides and proteins.
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