Journal Article10.1093/BRAIN/87.2.307
Alzheimer’s disease —an electron microscopical study
422
About: This article is published in Brain. The article was published on 01 Jun 1964. The article focuses on the topics: Amyloid & Cerebral cortex.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Axoplasmic alterations in the proximal and distal stumps of transsected nerves
S. Blümcke,H. R. Niedorf,J. Rode +2 more
TL;DR: During the early stage of axoplasmic degeneration, “dense lamellar bodies” appear in both the distal and the proximal stumps, followed by degeneration of mitochondria and neuroendoplasic reticulum (NER), and large “autolytic bodies’ develop.
88
Proteoglycans in the central nervous system: Role in development, neural repair, and Alzheimer's disease
TL;DR: The main functions of PGs in the CNS are reviewed as are the roles ofPGs in brain injury and in the development or treatment of AD.
84
Neuropathology of Alzheimer's disease.
TL;DR: The most important neuropathologic features of Alzheimer's disease, including amyloid plaques, neurofibrillary tangles, neuronal loss, synaptic depletion, cerebralAmyloid angiopathy, Hirano bodies, and granulovacuolar degeneration are summarized.
79
Alzheimer's disease: immunoreactivity of neurofibrillary tangles with anti-neurofilament and anti-paired helical filament antibodies.
C. G. Rasool,Carmela R. Abraham,Brian H. Anderton,Margaret Haugh,Jacob Kahn,Dennis J. Selkoe +5 more
TL;DR: It is concluded that neurofibrillary tangles in Alzheimer's disease are heterogeneous as regards their filamentous content and contain both antigen cross-reacting with neurofilaments and antigens which are apparently unique to PHF and not shared with normal neurofilament proteins.
79