Journal Article10.1016/J.BIOMATERIALS.2020.119827
Advances in nanomaterials for photodynamic therapy applications: Status and challenges.
Jianming Chen,Taojian Fan,Zhongjian Xie,Qiqiao Zeng,Ping Xue,Tingting Zheng,Yun Chen,Luo Xiaoling,Han Zhang +8 more
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TL;DR: The up-to-date advances in the fabrication and fascinating applications of various nanomaterials in PDT have been summarized, including various types of nanoparticles, carbon-based nanommaterials, and two-dimensional nanmaterials, etc.
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About: This article is published in Biomaterials. The article was published on 27 Jan 2020.
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Citations
Photodynamic Therapy Review: Principles, Photosensitizers, Applications, and Future Directions
José Higino Correia,José Higino Correia,José Alberto Rodrigues,Sara Pimenta,Tao Dong,Tao Dong,Zhaochu Yang +6 more
TL;DR: A review of the principles, mechanisms, photosensitizers, and current applications of photodynamic therapy can be found in this paper, where the future path on the research of new photosensizers with enhanced tumor selectivity, featuring the improvement of PDT effectiveness has also been addressed.
624
Conquering the Hypoxia Limitation for Photodynamic Therapy
TL;DR: In this article, a review of the recent progress in new nanomaterials designed to combat hypoxia and avoid the associated limitation of photodynamic therapy (PDT) is presented.
401
Recent Advances in Hyperthermia Therapy-Based Synergistic Immunotherapy.
TL;DR: The synergistic mechanism of HTT in immunotherapy, including immunogenic cell death and reversal of the immunosuppressive tumor microenvironment is discussed, and these strategies could achieve synergistically enhanced therapeutic outcomes against both primary tumors and metastatic lesions, prevent cancer recurrence, and prolong the survival period.
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Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy
Bin Ji,Minjie Wei,Bin Yan +2 more
TL;DR: The emerging nanomedicine-based strategies could subtly modulate the pharmacokinetics of therapeutic compounds and the TME to optimize both PDT and immunotherapy, resulting in an improved antitumor effect, and highlights the synergistic nanotherapeutics used to amplify immune responses combined with immunotherapy against tumors.
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Nanozymes-recent development and biomedical applications
TL;DR: Nanozyme is a series of nanomaterials with enzyme-mimetic activities that can proceed with the catalytic reactions of natural enzymes as discussed by the authors , which can be regulated by multiple factors, such as the chemical state of metal ion, pH, hydrogen peroxide (H2O2), and glutathione (GSH) level.
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TL;DR: In this article, the authors review recent progress in 2D materials in the terahertz domain and hybrid metamaterials with engineered functionalities through the incorporation of graphene, TMDs and BP.
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Enhancement of Photodynamic Cancer Therapy by Physical and Chemical Factors.
TL;DR: Some physicochemical factors that can make PDT a more viable and effective option in cancer therapy in order to provide future oncological patients with better-quality treatment options are summarized.
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TL;DR: It is shown that direct coupling of a dye-labelled DNA (acceptor) to a quantum dot (QD) donor significantly reduces the donor-acceptor distance and improves the FRET efficiency.
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The embedding of meta-tetra(hydroxyphenyl)-chlorin into silica nanoparticle platforms for photodynamic therapy and their singlet oxygen production and pH-dependent optical properties.
Fei Yan,Raoul Kopelman +1 more
TL;DR: In this paper, a modified Stober sol-gel process was used to embed a meta-tetra(hydroxyphenyl)-chlorin (m-THPC) inside a sol-gel matrix for photodynamic therapy.
Orthogonal near-infrared upconversion co-regulated site-specific O2 delivery and photodynamic therapy for hypoxia tumor by using red blood cell microcarriers.
TL;DR: An orthogonal near-infrared upconversion controlled red blood cell (RBC) microcarriers to selectively deliver O2 in hypoxia area and are capable of delivery a large amount of O2 for PDT under near- Infrared (NIR) irradiation to realize effective solid tumor eradication.
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