Journal Article10.1016/J.BIOMATERIALS.2020.119827
Advances in nanomaterials for photodynamic therapy applications: Status and challenges.
Jianming Chen,Taojian Fan,Zhongjian Xie,Qiqiao Zeng,Ping Xue,Tingting Zheng,Yun Chen,Luo Xiaoling,Han Zhang +8 more
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TL;DR: The up-to-date advances in the fabrication and fascinating applications of various nanomaterials in PDT have been summarized, including various types of nanoparticles, carbon-based nanommaterials, and two-dimensional nanmaterials, etc.
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About: This article is published in Biomaterials. The article was published on 27 Jan 2020.
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Citations
Photodynamic Therapy Review: Principles, Photosensitizers, Applications, and Future Directions
José Higino Correia,José Higino Correia,José Alberto Rodrigues,Sara Pimenta,Tao Dong,Tao Dong,Zhaochu Yang +6 more
TL;DR: A review of the principles, mechanisms, photosensitizers, and current applications of photodynamic therapy can be found in this paper, where the future path on the research of new photosensizers with enhanced tumor selectivity, featuring the improvement of PDT effectiveness has also been addressed.
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Conquering the Hypoxia Limitation for Photodynamic Therapy
TL;DR: In this article, a review of the recent progress in new nanomaterials designed to combat hypoxia and avoid the associated limitation of photodynamic therapy (PDT) is presented.
401
Recent Advances in Hyperthermia Therapy-Based Synergistic Immunotherapy.
TL;DR: The synergistic mechanism of HTT in immunotherapy, including immunogenic cell death and reversal of the immunosuppressive tumor microenvironment is discussed, and these strategies could achieve synergistically enhanced therapeutic outcomes against both primary tumors and metastatic lesions, prevent cancer recurrence, and prolong the survival period.
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Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy
Bin Ji,Minjie Wei,Bin Yan +2 more
TL;DR: The emerging nanomedicine-based strategies could subtly modulate the pharmacokinetics of therapeutic compounds and the TME to optimize both PDT and immunotherapy, resulting in an improved antitumor effect, and highlights the synergistic nanotherapeutics used to amplify immune responses combined with immunotherapy against tumors.
282
Nanozymes-recent development and biomedical applications
TL;DR: Nanozyme is a series of nanomaterials with enzyme-mimetic activities that can proceed with the catalytic reactions of natural enzymes as discussed by the authors , which can be regulated by multiple factors, such as the chemical state of metal ion, pH, hydrogen peroxide (H2O2), and glutathione (GSH) level.
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Graphitic-phase C3N4 nanosheets as efficient photosensitizers and pH-responsive drug nanocarriers for cancer imaging and therapy
TL;DR: It is proven for the first time that g-C3N4 nanosheets can be used as efficient photosensitizers for photodynamic tumor therapy and as pH-responsive nanocarriers for drug delivery.
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TL;DR: The major issue of the degradation encountered in realizing devices based on few‐layered black phosphorus and phosphorene is reviewed and its significance is discussed, as well as ways to advance state‐of‐art ofosphorene‐based devices.
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WS2 nanosheet as a new photosensitizer carrier for combined photodynamic and photothermal therapy of cancer cells.
Yuan Yong,Liangjun Zhou,Zhanjun Gu,Liang Yan,Gan Tian,Gan Tian,Xiaopeng Zheng,Xiaodong Liu,Xiao Zhang,Junxin Shi,Junxin Shi,Wenshu Cong,Wenyan Yin,Yuliang Zhao +13 more
TL;DR: The results clearly showed that the efficacy of combined PDT-PTT treatment of cancer cells is significantly higher than those of PDT-only and PTT-only treatment, indicating enhanced efficiency of the combined therapeutic system.
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Nanostructured Phthalocyanine Assemblies with Protein-Driven Switchable Photoactivities for Biophotonic Imaging and Therapy
Xingshu Li,C-Yoon Kim,Seunghyun Lee,Dayoung Lee,Hyung-Min Chung,Gyoungmi Kim,Si-Hyun Heo,Chulhong Kim,Ki-Sung Hong,Juyoung Yoon +9 more
TL;DR: A "one-for-all" nanomaterial that self-assembles from flexible and versatile phthalocyanine building blocks that has a high selectivity for biotin receptor-positive cancer cells, and permits a combined photodynamic and photothermal therapeutic effect.
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In vivo studies of fullerene-based materials using endohedral metallofullerene radiotracers
TL;DR: The present findings demonstrate the feasibility of using water-solubilized metallofullerene radiotracers to monitor the fate of fullerene-based materials in animals, and suggest that water- solvent-based fullerenes, in general, may be useful components in drug design.
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