Advances in nanomaterials for photodynamic therapy applications: Status and challenges.

TL;DR: In this article, a review of the recent progress in new nanomaterials designed to combat hypoxia and avoid the associated limitation of photodynamic therapy (PDT) is presented.

TL;DR: The synergistic mechanism of HTT in immunotherapy, including immunogenic cell death and reversal of the immunosuppressive tumor microenvironment is discussed, and these strategies could achieve synergistically enhanced therapeutic outcomes against both primary tumors and metastatic lesions, prevent cancer recurrence, and prolong the survival period.

TL;DR: The emerging nanomedicine-based strategies could subtly modulate the pharmacokinetics of therapeutic compounds and the TME to optimize both PDT and immunotherapy, resulting in an improved antitumor effect, and highlights the synergistic nanotherapeutics used to amplify immune responses combined with immunotherapy against tumors.

TL;DR: Nanozyme is a series of nanomaterials with enzyme-mimetic activities that can proceed with the catalytic reactions of natural enzymes as discussed by the authors , which can be regulated by multiple factors, such as the chemical state of metal ion, pH, hydrogen peroxide (H2O2), and glutathione (GSH) level.

TL;DR: The rational design of a Hf–porphyrin nanoscale metal–organic framework, DBP–UiO, as an exceptionally effective photosensitizer for PDT of resistant head and neck cancer represents a new class of highly potent PDT agents and hold great promise in treating resistant cancers in the clinic.

TL;DR: Dr. W. Bu Jiangsu Collaborative Innovation Center for Advanced Inorganic Functional Composites Nanjing Tech University Nanjing 210009 and Prof. J. Shi State Key Laboratory of High Performance Ceramics and Superfi ne Microstructures Shanghai Institute of Ceramic Chinese Academy of Sciences Shanghai 200050.

TL;DR: The recent advances made with graphene‐related materials in the biomedical field and the challenges facing these exciting new tools both in terms of biological activity and toxicological profiling in vitro and in vivo are described.

TL;DR: A surface plasmon resonance sensor based on two-dimensional nanomaterial of antimonene for the specific label-free detection of clinically relevant biomarkers such as miRNA-21 and mi RNA-155 and provides a promising avenue for the early diagnosis, staging, and monitoring of cancer.