Journal Article10.1002/ADHM.201700845
Advances in Magnetic Nanoparticles for Biomedical Applications.
Vanessa Fernandes Cardoso,A. Francesko,Clarisse Ribeiro,Manuel Bañobre-López,Pedro Martins,Senentxu Lanceros-Méndez +5 more
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TL;DR: The present work addresses the structure, synthesis, properties, and the incorporation of magnetic NPs in nanocomposites, highlighting the most relevant effects of the synthesis on the magnetic and structural properties of the magnet NPs and how these effects limit their utilization in the biomedical area.
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Abstract: V.F.C. and A.F. contributed equally to this work. The authors thank the FCT—Fundacao para a Ciencia e Tecnologia—for financial support under framework of the Strategic Funding UID/FIS/04650/2013, project PTDC/ EEI-SII/5582/2014 and project UID/EEA/04436/2013 by FEDER funds through the COMPETE 2020—Programa Operacional Competitividade e Internacionalizacao (POCI). Funds provided by FCT in the framework of EuroNanoMed 2016 call, Project LungChek ENMed/0049/2016 are also gratefully acknowledged. V.F.C., A.F., C.R., and P.M. also thank the FCT for the grants SFRH/BPD/98109/2013, SFRH/BPD/104204/2014, SFRH/ BPD/90870/2012 and SFRH/BPD/96227/2013, respectively. Finally, the authors acknowledge funding by the Spanish Ministry of Economy and Competitiveness (MINECO) through the project MAT2016-76039C4-3-R (AEI/FEDER, UE) and from the Basque Government Industry Department under the ELKARTEK program.
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References
Superparamagnetic Nanocomposites Based on the Dispersion of Oleic Acid-Stabilized Magnetite Nanoparticles in a Diglycidylether of Bisphenol A-Based Epoxy Matrix: Magnetic Hyperthermia and Shape Memory
Julieta Puig,Cristina Elena Hoppe,Laura Alejandra Fasce,Claudio Javier Pérez,Yolanda Piñeiro-Redondo,Manuel Bañobre-López,M. A. López-Quintela,José Rivas,Roberto J. J. Williams +8 more
TL;DR: In this article, superparamagnetic nanocomposites were obtained by dispersion of oleic acid-coated magnetite NPs in an epoxy system based on diglycidylether of bisphenol A (DGEBA) modified with OA.
80
Catechol-Functionalized Chitosan/Iron Oxide Nanoparticle Composite Inspired by Mussel Thread Coating and Squid Beak Interfacial Chemistry
TL;DR: This report reports on the synthesis and preparation of bioinspired organic/inorganic composites that mimic the key physicochemical features associated with the mechanical strengthening of both squid beaks and mussel thread coatings using chitosan as an initial template.
80
A Systematic Study of the Structural and Magnetic Properties of Mn-, Co-, and Ni-Doped Colloidal Magnetite Nanoparticles
Francis Leonard Deepak,Manuel Bañobre-López,Enrique Carbó-Argibay,M. Fátima Cerqueira,Y. Piñeiro-Redondo,José Rivas,Corey M. Thompson,Saeed Kamali,Carlos F. Rodríguez-Abreu,Kirill Kovnir,Yury V. Kolen’ko +10 more
- 14 May 2015
TL;DR: A systematic study of structural and magnetic properties of Mn-, Co-, and Ni-doped colloidal magnetite nanoparticles reveals the formation of chemically uniform single-phase solid solution nanoparticles with cubic spinel structure. The local structure of the Fe3O4 NPs is distorted with respect to the cubic inverse-spinel structure, and chemical substitution of Fe by Mn or Ni partially eliminates the local distortions.
79
Receptor-targeted, magneto-mechanical stimulation of osteogenic differentiation of human bone marrow-derived mesenchymal stem cells.
TL;DR: It was found that a higher mineral-to-matrix ratio was obtained after three weeks of magneto-mechanical stimulation coupled with osteogenic medium culture by initially targeting PDGFRα compared with targeting integrin ανβ3 and non-treated controls.
78
Magnetically actuated tissue engineered scaffold: insights into mechanism of physical stimulation
Yulia Sapir-Lekhovitser,Menahem Y. Rotenberg,Juergen Jopp,Gary Friedman,Boris Polyak,Smadar Cohen +5 more
TL;DR: The results show that magnetically responsive scaffolds exposed to an externally applied time-varying uniform magnetic field undergo a reversible shape deformation, and suggest that the matrix structure deformation is produced by immobilized magnetic nanoparticles within the matrix walls resulting in a collective alignment of scaffold walls upon magnetization.