Journal Article10.1080/14653240310003026
Adipose-derived adult stem cells: isolation, characterization, and differentiation potential
Jeffrey M. Gimble,Farshid Guilak +1 more
1.2K
TL;DR: Adipose tissue is an abundant, accessible, and replenishable source of adult stem cells that can be isolated from liposuction waste tissue by collagenase digestion and differential centrifugation, and these ADAS cells have potential applications for the repair and regeneration of acute and chronically damaged tissues.
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About: This article is published in Cytotherapy. The article was published on 01 Jan 2003. The article focuses on the topics: Stem cell transplantation for articular cartilage repair & Adult stem cell.
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Citations
Adipose derived stem cells and nerve regeneration.
TL;DR: A review examines the potential of adipose-derived stem cells to improve nerve repair assisted by bioengineered nerve grafts and concludes that stem cells are prime candidates as accelerators of regeneration in these nerve graftS.
Myogenic Differentiation of Mesenchymal Stem Cells for Muscle Regeneration in Urinary Tract.
Yang Bin,Zheng Jun-hua,Zhang Yuan-yuan +2 more
TL;DR: Adult mesenchymal stem cells can differentiate into smooth and skeletal muscle cells, restoring urinary muscle tissue and improving quality of life in patients with urinary tract disorders through regenerative medicine technology.
Lipotransfer: the potential from bench to bedside.
Ilaria Tocco,Alan D. Widgerow,Shadi Lalezari,Derek A. Banyard,Ashkaun Shaterian,Gregory R. D. Evans +5 more
TL;DR: Current available literature still provides some evidence for optimal results in differing clinical scenarios, in the wait of validating andultimate studies, and recent studies have brought us closer to making informed decisions on technical choices in lipotransfer.
An immortalized human adipose-derived stem cell line with highly enhanced chondrogenic properties.
TL;DR: The goal of this study was to create an immortalized ASC line that showed enhanced and consistent chondrogenic potential for applications in cartilage tissue engineering as well as to provide a platform for investigation of biological and mechanobiological pathways involved incartilage homeostasis and disease.
Periodontal tissue regeneration by transplantation of rat adipose-derivedstromal cells in combination with PLGA-based solid scaffolds
Daisuke Akita,Masakazu Morokuma,Yoko Saito,Katsuyuki Yamanaka,Yuko Akiyama,Momoko Sato,Takayuki Mashimo,Taku Toriumi,Yoshinori Arai,Tadashi Kaneko,Naoki Tsukimura,Keitaro Isokawa,Tomohiko Ishigami,Masaki J Hond +13 more
TL;DR: The present investigation demonstrated the marked ability of ASCs in combination with PLGA scaffolds to repair periodontal defects.
References
Multilineage Potential of Adult Human Mesenchymal Stem Cells
Mark F. Pittenger,Alastair Morgan Mackay,Stephen C. Beck,Rama K. Jaiswal,Robin Douglas,Joseph D. Mosca,Mark Aaron Moorman,Donald William Jr. Ward Road Simonetti,Stewart Craig,Daniel R. Marshak +9 more
TL;DR: Adult stem cells isolated from marrow aspirates of volunteer donors could be induced to differentiate exclusively into the adipocytic, chondrocytic, or osteocytic lineages.
22K
Multilineage cells from human adipose tissue: implications for cell-based therapies.
Patricia A. Zuk,Min Zhu,Hiroshi Mizuno,Jerry I. Huang,Futrell Jw,Adam J. Katz,Prosper Benhaim,H. P. Lorenz,Marc H. Hedrick +8 more
TL;DR: The data support the hypothesis that a human lipoaspirate contains multipotent cells and may represent an alternative stem cell source to bone marrow-derived MSCs.
Human Adipose Tissue Is a Source of Multipotent Stem Cells
Patricia A. Zuk,Min Zhu,Peter Ashjian,Daniel A. De Ugarte,Jerry I. Huang,Hiroshi Mizuno,Zeni Alfonso,John K. Fraser,Prosper Benhaim,Marc H. Hedrick +9 more
TL;DR: To confirm whether adipose tissue contains stem cells, the PLA population and multiple clonal isolates were analyzed using several molecular and biochemical approaches and PLA cells exhibited unique characteristics distinct from those seen in MSCs, including differences in CD marker profile and gene expression.
The Metabolism of Isolated Fat Cells: I. Effects of Hormones on Glucose Metabolism and Lipolysis
Martin Rodbell
- 01 Feb 1964
TL;DR: This article marks the beginning of Rodbell's interest in cell receptors and related his discovery that fat cells could be isolated from other cells by treating them with preparations of collagenase, and also found that insulin could stimulate glucose uptake.
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