Journal Article10.1080/14653240310003026
Adipose-derived adult stem cells: isolation, characterization, and differentiation potential
Jeffrey M. Gimble,Farshid Guilak +1 more
1.2K
TL;DR: Adipose tissue is an abundant, accessible, and replenishable source of adult stem cells that can be isolated from liposuction waste tissue by collagenase digestion and differential centrifugation, and these ADAS cells have potential applications for the repair and regeneration of acute and chronically damaged tissues.
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About: This article is published in Cytotherapy. The article was published on 01 Jan 2003. The article focuses on the topics: Stem cell transplantation for articular cartilage repair & Adult stem cell.
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Citations
Imaging the cytoskeleton in live Xenopus laevis embryos.
TL;DR: An approach to image the cytoskeleton in embryos of the frog, Xenopus laevis, using mRNA to express fluorescently tagged cytoskeletal probes and confocal microscopy to visualize their dynamic behavior is described.
Photocrosslinked alginate with hyaluronic acid hydrogels as vehicles for mesenchymal stem cell encapsulation and chondrogenesis.
TL;DR: This study demonstrates the utility of photocrosslinked, injectable alginate hydrogels containing interpenetrating hyaluronic acid chains to support stem cell chondrogenesis and shows significant potential for cell-based cartilage repair therapies.
Enhanced survival and function of islet-like clusters differentiated from adipose stem cells on a three-dimensional natural polymeric scaffold: an in vitro study.
AloysiousNeena,D NairPrabha +1 more
TL;DR: A three-dimensional (3D) biodegradable scaffold comprised of natural polymers dextran and gelatin (DEXGEL) for differentiation of adipose stem cells to islet-like clusters (ILCs) is fabricated.
3D bioprinting for tissue engineering: Stem cells in hydrogels
Nazia Mehrban,Gui Zhen Teoh,Martin A. Birchall +2 more
- 01 Jan 2016
TL;DR: 3D bioprinting offers precision control as well as the ability to incorporate biological cues and cells directly into the material as it is being fabricated, which is crucial in building more complex systems that morphologically and functionally mimic in vivo tissue.
Stem cell therapies in tendon-bone healing
TL;DR: In this article, a review on the current circumstances of tendon-bone healing using stem cell therapy is presented, focusing on the tendon insertion injury and the success of this reconstructive process depends on the ability of the graft to incorporate into the bone.
References
Multilineage Potential of Adult Human Mesenchymal Stem Cells
Mark F. Pittenger,Alastair Morgan Mackay,Stephen C. Beck,Rama K. Jaiswal,Robin Douglas,Joseph D. Mosca,Mark Aaron Moorman,Donald William Jr. Ward Road Simonetti,Stewart Craig,Daniel R. Marshak +9 more
TL;DR: Adult stem cells isolated from marrow aspirates of volunteer donors could be induced to differentiate exclusively into the adipocytic, chondrocytic, or osteocytic lineages.
22K
Multilineage cells from human adipose tissue: implications for cell-based therapies.
Patricia A. Zuk,Min Zhu,Hiroshi Mizuno,Jerry I. Huang,Futrell Jw,Adam J. Katz,Prosper Benhaim,H. P. Lorenz,Marc H. Hedrick +8 more
TL;DR: The data support the hypothesis that a human lipoaspirate contains multipotent cells and may represent an alternative stem cell source to bone marrow-derived MSCs.
Human Adipose Tissue Is a Source of Multipotent Stem Cells
Patricia A. Zuk,Min Zhu,Peter Ashjian,Daniel A. De Ugarte,Jerry I. Huang,Hiroshi Mizuno,Zeni Alfonso,John K. Fraser,Prosper Benhaim,Marc H. Hedrick +9 more
TL;DR: To confirm whether adipose tissue contains stem cells, the PLA population and multiple clonal isolates were analyzed using several molecular and biochemical approaches and PLA cells exhibited unique characteristics distinct from those seen in MSCs, including differences in CD marker profile and gene expression.
The Metabolism of Isolated Fat Cells: I. Effects of Hormones on Glucose Metabolism and Lipolysis
Martin Rodbell
- 01 Feb 1964
TL;DR: This article marks the beginning of Rodbell's interest in cell receptors and related his discovery that fat cells could be isolated from other cells by treating them with preparations of collagenase, and also found that insulin could stimulate glucose uptake.
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