Abnormal brain synchrony in Down Syndrome

TL;DR: This article assessed top-down contributions of memory representations to figure-ground perceptivity, and found that memory representations may guide basic perceptual functions, such as figure ground perception, in three studies.

TL;DR: In this paper , the authors used fALFF and regional homogeneity (ReHo) strategies to find differences in spontaneous brain activity among young people with Down syndrome and controls and to correlate these results with cognitive outcomes.

TL;DR: A neurocomputational model for investigating the role of dopamine level on the synchronized behavior of medium spiny neurons in striatum shows that dopamine level has opposite effect on the synchronization of D1 and D2 type medium sp Tiny neuron populations and it is shown that spike timing dependent plasticity enhances the synchronized Behavior.

TL;DR: Different aspects of DS are reviewed and the results of DS treatment in an animal model, namely the Ts65Dn mouse are analyzed to encourage more efforts to improve the quality of life to people affected by DS.

TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.

TL;DR: Construction of brain networks from connectivity data is discussed and the most commonly used network measures of structural and functional connectivity are described, which variously detect functional integration and segregation, quantify centrality of individual brain regions or pathways, and test resilience of networks to insult.

TL;DR: It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.

TL;DR: It is suggested that both task-driven neuronal responses and behavior are reflections of this dynamic, ongoing, functional organization of the brain, featuring the presence of anticorrelated networks in the absence of overt task performance.