Journal Article10.1111/PAPR.12544
A Prospective Study Comparing Platelet-Rich Plasma and Local Anesthetic (LA)/Corticosteroid in Intra-Articular Injection for the Treatment of Lumbar Facet Joint Syndrome
Jiu-Ping Wu,Jingjing Zhou,Chibing Liu,Jun Zhang,Xiong Wei,Yang Lv,Rui Liu,Ruiqiang Wang,Zhenwu Du,Guizhen Zhang,Qinyi Liu +10 more
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TL;DR: To compare the effectiveness and safety between autologous platelet‐rich plasma (PRP) and Local Anesthetic (LA)/corticosteroid in intra‐articular injection for the treatment of lumbar facet joint syndrome.
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Abstract: Objectives To compare the effectiveness and safety between autologous platelet-rich plasma (PRP) and Local Anesthetic (LA)/corticosteroid in intra-articular injection for the treatment of lumbar facet joint syndrome. Methods Forty-six eligible patients with lumbar facet joint syndrome were randomized into group A (intra-articular injection with PRP) and group B (intra-articular injection with LA/corticosteroid). The following contents were evaluated: pain visual analog scale (VAS) at rest and during flexion, and the Roland-Morris Disability Questionnaire (RMQ), Oswestry Disability Index (ODI), and modified MacNab criteria for pain relief and applications of post-treatment drugs. All outcome assessments were performed immediately after and at 1 week, 1, 2, 3, and 6 months after treatment. Results No significant difference between groups was observed at baseline. Compared with pretreatment, both group A and group B demonstrated statistical improvements in the pain VAS score at rest or during flexion, the RMQ, and the ODI (P Conclusions Both autologous PRP and LA/corticosteroid for intra-articular injection are effective, easy, and safe enough in the treatment of lumbar facet joint syndrome. However, autologous PRP is a superior treatment option for longer duration efficacy.
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Citations
Facet joint syndrome: from diagnosis to interventional management
Romain Perolat,Adrian Kastler,Benjamin Nicot,Jean-Michel Pellat,Florence Tahon,Arnaud Attyé,Olivier Heck,Kamel Boubagra,Sylvie Grand,Alexandre Krainik +9 more
TL;DR: The anatomy, epidemiology, clinical presentation, and radiologic findings of facet joint syndrome are described and patients may benefit from specific interventions to eliminate facet joint pain such as neurolysis by radiofrequency or cryoablation.
The use of lumbar epidural injection of platelet lysate for treatment of radicular pain
Christopher J. Centeno,Jason Markle,Ehren Dodson,Ian Stemper,Matthew Hyzy,Christopher J. Williams,Michael D. Freeman +6 more
TL;DR: Patients treated with PL epidurals reported significant improvements in pain, exceeded the minimal clinically important difference (MCID) for FRI, and reported subjective improvement through 2-year follow-up, suggesting PL may be a promising substitute for corticosteroid.
The American Society of Pain and Neuroscience (ASPN) Evidence-Based Clinical Guideline of Interventional Treatments for Low Back Pain
Dawood Sayed,Jay S. Grider,Natalie Strand,Jonathan M Hagedorn,Steven M. Falowski,Christopher M Lam,Vinicius Tieppo Francio,Douglas P. Beall,Nestor D. Tomycz,Justin Davanzo,Rohit Aiyer,David W. Lee,H. Kalia,S. Sheen,Mark Malinowski,Michael H. Verdolin,Shashank Vodapally,Alexios G. Carayannopoulos,Sameer Kumar Jain,Nomen Azeem,Reda Tolba,George C. Chang Chien,Priyanka Ghosh,Anthony J Mazzola,Kasra Amirdelfan,Krishnan Chakravarthy,Erika A. Petersen,Michael E. Schatman,Tim Deer +28 more
TL;DR: The ASPN Back Guideline as mentioned in this paper provides clinicians with a comprehensive review of interventional treatments for lower back disorders, evaluating the appropriateness, effectiveness, and safety of these treatments.
Treatment of symptomatic degenerative intervertebral discs with autologous platelet-rich plasma: follow-up at 5-9 years.
TL;DR: A subset of patients who received intradiscal platelet-rich plasma (PRP) injections for moderate-to-severe lumbar discogenic pain demonstrated statistically and clinically significant improvements in pain and function at 5-9 years postinjection.
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A Randomized Double-Blind Controlled Pilot Study Comparing Leucocyte-Rich Platelet-Rich Plasma and Corticosteroid in Caudal Epidural Injection for Complex Chronic Degenerative Spinal Pain.
Ricardo Ruiz-Lopez,Yu-Chuan Tsai +1 more
TL;DR: To compare the efficacy and safety between leucocyte‐rich platelet‐rich plasma (LR‐PRP) and corticosteroid in fluoroscopically guided caudal epidural injection for patients with complex chronic lumbar spinal pain.
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